Results 151 to 160 of about 177,236 (307)

New Biologic and Small Molecule Therapies for Hidradenitis Suppurativa

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Hidradenitis suppurativa (HS) is an inflammatory skin disease that has historically been underdiagnosed and, until recently, under‐researched. Furthermore, the pathophysiology of HS is complex, and not fully understood. Just three biologic medications—adalimumab (anti‐TNF‐α), secukinumab (anti‐IL17A) and bimekizumab (anti‐IL17A/F) are licensed
Emily Pender   +2 more
wiley   +1 more source

Links Between Social Support, Thwarted Belongingness, and Suicide Ideation among Lesbian, Gay, and Bisexual College Students [PDF]

open access: yes, 2017
Emerging adults with a lesbian, gay, or bisexual (LGB) identity are at greater risk for engaging in suicide-related behaviors. This disparity highlights a need to elucidate specific risk and protective factors associated with suicide-related behaviors ...
Hill, Ryan M   +3 more
core   +1 more source

Mental Health Among Caregivers of Children With Atopic Dermatitis: A Systematic Review With Meta‐Analysis

open access: yesJEADV Clinical Practice, EarlyView.
This systematic review and meta‐analysis aimed to examine the association between child atopic dermatitis and caregiver mental health. Fifteen observational studies were identified through PubMed, EMBASE, and Web of Science, excluding non‐English publications, clinical trials, and case reports.
Hannah Kang   +6 more
wiley   +1 more source

Clinical Outcome Assessments in Parkinson's Disease: A Scoping Review of Current Rating Scales and Future Needs

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Clinical outcome assessments (COAs) are essential for evaluating symptom severity, treatment response, and disease progression in Parkinson's disease (PD). As clinical knowledge evolves, it is necessary to revisit the recommendation status on the COAs to ensure their continued relevance and validity. Objectives To provide an updated
Evita Papathoma   +14 more
wiley   +1 more source

‘I don't know what is autism, what is normal teenage behaviour, and what is naughtiness’: Conceptualising child and adolescent to parent violence in the context of neurodevelopmental difference

open access: yesChildren &Society, EarlyView., 2023
Abstract This article presents findings from a UK‐based qualitative study that explored parents/carers experiences of child to parent violence (CPV) from their child who has a neurodevelopmental difference. The study used semi‐structured interviews with 15 mothers who were experiencing physical and psychological violence from their child, often on a ...
Amanda Holt
wiley   +1 more source

The Hidden Burden of Hemifacial Spasm: A Systematic Review of Non‐Motor Symptoms

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Hemifacial spasm (HFS) is a chronic neurological disorder characterized by involuntary contractions of facial muscles. Traditionally regarded as a motor condition, HFS encompasses a spectrum of non‐motor symptoms that are often overlooked but significantly affect patients’ quality of life.
Miriam Carvalho Soares   +2 more
wiley   +1 more source

An Open‐Label Phase 1b Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of ANX005 in Patients with Huntington's Disease

open access: yesMovement Disorders, EarlyView.
Complement activation is implicated in Huntington's disease; ANX005 is a potent inhibitor of component C1q. ANX005 exhibited a generally manageable safety profile with rapid reduction in C1q in the cerebrospinal fluid. Functional ability on composite Unified Huntington's Disease Rating Scale and total functional capacity was maintained, with potential ...
Rajeev Kumar   +15 more
wiley   +1 more source

COUNSELLING STRATEGIES FOR REDUCING DEPRESSION AND SUICIDAL IDEATION AMONG STUDENTS OF TERTIARY INSTITUTIONS IN NIGERIA [PDF]

open access: yesAnnals of the University of Craiova for Journalism, Communication and Management
Students undergo a significant transitional phase from adolescence to adulthood, which is widely recognized as one of the most challenging periods in an individual's life.
Rasaq Abimbola FADIPE   +1 more
doaj  

Exploring Suicide Prevention Gatekeeper Interventions for Schools: A Scoping Review

open access: yesPsychology in the Schools, EarlyView.
ABSTRACT Background Among teenagers and young adults, suicide represents a significant public health challenge. Schools are critical for suicide prevention due to the significant time adolescents spend there. Gatekeeper training (GKT) has shown promise in increasing awareness and knowledge, but its implementation‑relevant characteristics and contextual
Lena Rossen Østergaard   +4 more
wiley   +1 more source

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