Results 261 to 270 of about 295,290 (360)

Efficacy of combined varenicline and nicotine replacement therapy compared with varenicline or nicotine replacement therapy alone for smoking cessation: A systematic review and meta‐analysis

open access: yesAddiction, EarlyView.
Abstract Aims To assess whether combining nicotine replacement therapy (NRT) with varenicline improves long‐term smoking cessation rates compared with varenicline or NRT alone. Method Systematic review and meta‐analysis of randomized controlled trials (RCTs) or quasi‐RCTs, conducted according to PRISMA guidelines.
Xinmei Zhou   +18 more
wiley   +1 more source

5‐Methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) for alcohol use disorder: An open‐label, phase 2, proof‐of‐concept, clinical trial

open access: yesAddiction, EarlyView.
Abstract Background and Aims Psychedelic drugs may help treat alcohol use disorder (AUD). This study evaluated BPL‐003, a novel intranasal powder formulation of 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) benzoate salt, in people with moderate–severe AUD enrolled in a standard of care, 10‐week programme of relapse‐prevention oriented Cognitive ...
John Marsden   +10 more
wiley   +1 more source

The Effect of a Single Dose of Intravenous Ketamine on Suicidal Ideation: A Systematic Review and Individual Participant Data Meta-Analysis.

open access: yesAmerican Journal of Psychiatry, 2017
S. Wilkinson   +9 more
semanticscholar   +1 more source

Varenicline for cannabis use disorder: A randomized controlled trial

open access: yesAddiction, EarlyView.
Abstract Background and aims Although cannabis use is widespread and prevalence of cannabis use disorder (CUD) is increasing, limited advancements have been made in CUD medication development. The objective of this study was to test the efficacy of varenicline with medical management for reducing cannabis use in treatment‐seeking individuals with CUD ...
Aimee L. McRae‐Clark   +8 more
wiley   +1 more source

Substance use and sexual orientation among adolescents: Differences by age group and sex in the 2023 National Survey of Drug Use and Health

open access: yesThe American Journal on Addictions, EarlyView.
Abstract Background and Objectives Adolescent substance use is a critical public health concern with significant long‐term consequences, yet research on disparities by sexual orientation remains limited. Despite the unique stressors faced by sexual minority youth—particularly bisexual individuals—that increase their risk for substance use, most studies
Timothy J. Grigsby   +5 more
wiley   +1 more source

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