Results 51 to 60 of about 97,977 (299)

Forming ideal types by understanding. Application to the psychoanalytic treatment of suicidal men [PDF]

, 2010
This paper discusses the application of a qualitative methodology—forming ideal types by understanding—to the psychoanalytic psychotherapy of suicidal men. The paper focuses on a particular phase of the methodology: the validation through external expert
Briggs, Stephen, Lindner, Reinhard
core  

Predictors of response to cognitive-behavioral therapy for body dysmorphic disorder [PDF]

, 2019
Body dysmorphic disorder (BDD) is a common and distressing or impairing preoccupation with a perceived defect in physical appearance. Individuals with BDD engage in time-consuming rituals to check, hide, or "fix" their appearance or alleviate distress ...
Greenberg, Jennifer L., Hoeppner, Susanne S., Phillips, Katharine A., Steketee, Gail, Wilhelm, Sabine   +4 more
core   +1 more source

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

Advanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann, Theresa M. Wierschin, Stefanie Kretschmer, Banaja P. Dash, Aaron Held, Andrea Salzinger, Kevin Peikert, Anže Karlek, Hannes Glaß, Dajana Großmann, René Günther, Susanne Petri, Annekathrin Rödiger, David Brenner, Francisco Pan‐Montojo, Eleonora Aronica, Markus Kipp, Vitaly Zimyanin, Jared Sterneckert, Torsten Grehl, Noah D. Seebacher, Tobias M. Böckers, Alberto Catanese, Brian J. Wainger, Patrick Oeckl, Min Ae Lee‐Kirsch, Andreas Hermann   +26 more
wiley   +1 more source

Knowledge, attitudes, and experiences in suicide assessment and management: a qualitative study among primary health care workers in southwestern Uganda

BMC Psychiatry, 2022
Background Suicide is one of the leading causes of death globally, with over 75% of all suicides occurring in low-and middle-income Countries. Although 25% of people have contact with their health care workers before suicide attempts, most never receive ...
Godfrey Z. Rukundo, Edith K. Wakida, Samuel Maling, Mark M. Kaggwa, Baker M. Sserumaga, Letizia M. Atim, Clara D. Atuhaire, Celestino Obua   +7 more
doaj   +1 more source

The risk-taking and self-harm inventory for adolescents: Development and psychometric evaluation [PDF]

, 2010
In this study, we report on the development and psychometric evaluation of the Risk-Taking (RT) and Self-Harm (SH) Inventory for Adolescents (RTSHIA), a self-report measure designed to assess adolescent RT and SH in community and clinical settings.
Fearon, Pasco R. M., Fonagy, Peter, Roussow, Trudie, Vrouva, Ioanna   +3 more
core   +1 more source

A Glucose‐Responsive Intelligent Antibacterial and Oxygen‐Producing Hydrogel Promotes the Healing of Diabetic Wounds by Regulating Cellular Heterogeneity

Advanced Science, EarlyView.
We have developed a glucose‐triggered on‐demand drug delivery CF‐CPGaMPN hydrogel based on borate ester bonds. It inactivates microbes, releases oxygen, and enables on‐demand drug release in high‐glucose environments to promote healing of diabetic wounds. Single‐cell sequencing reveals that the CF‐CPGaMPN hydrogel significantly alleviates dysfunctional
Manxuan Liu, Zhongcheng Li, Qian Ren, Ziqian Lu, Yubing Zhang, Yili Guo, Ruomeng Li, Die Hu, Linglin Zhang   +8 more
wiley   +1 more source

Immunological correlates of suicidality among adolescents with internalizing symptoms

Brain, Behavior, & Immunity - Health
Background: Suicide is a leading cause of death in adolescents and young adults globally. Well-established risk factors for suicide are depression and past suicide attempts.
Chloe Roske, Tram N.B. Nguyen, Joshua J. Schwartz, Ava Erulker, Kai Nie, Hui Xie, Seunghee Kim-Schulze, Benjamin A. Ely, Russell H. Tobe, Wenzhu Mowrey, Vilma Gabbay   +10 more
doaj   +1 more source

Suicidality among Chinese college students: A cross-sectional study across seven provinces.

PLoS ONE, 2020
BackgroundAlthough the suicide rate in China has decreased over the past 20 years, there have been reports that the younger age group has been experiencing an increased incidence of completed suicide.
Bob Lew, Kairi Kõlves, Augustine Osman, Mansor Abu Talib, Norhayati Ibrahim, Ching Sin Siau, Caryn Mei Hsien Chan   +6 more
doaj   +1 more source

Religious affiliation and suicidality among college students in China: A cross-sectional study across six provinces.

PLoS ONE, 2021
BackgroundSeveral past studies indicated that religious beliefs, orientation, and practice are protective of suicide. Findings from recent studies in China suggest that religiosity may contribute to increased suicidality.
Bob Lew, Kairi Kõlves, Jie Zhang, Wang Zhizhong, Harold G Koenig, Paul S F Yip, Mansor Abu Talib, Augustine Osman, Ching Sin Siau, Caryn Mei Hsien Chan   +9 more
doaj   +1 more source

Effectiveness of Pre‐Transplant Dual GLP‐1 Receptor Agonist and SGLT2 Inhibitor Therapy on All‐Cause Mortality in Organ Transplantation Candidates with Obesity and Type 2 Diabetes: a Target‐Trial Emulation

Advanced Science, EarlyView.
This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang, Min‐Yu Tsou, Pin‐Hung Li, Jo‐Ching Chen, Yen‐Liang Liu, Gideon Meyerowitz‐Katz, Tsung‐Hsun Tsai, Pen‐Hua Su   +7 more
wiley   +1 more source