Results 131 to 140 of about 979,283 (258)

Next‐Generation CAR‐T Cell Therapy: From Modular Design to Clinical Expansion

open access: yesExploration, EarlyView.
Over the past decades, chimeric antigen receptor (CAR)‐T cell therapy has evolved from a linear engineering concept into a powerful yet constrained immunotherapy, limited by tumour microenvironment barriers, immune evasion, and manufacturing complexity.
Yuesong Bai   +5 more
wiley   +1 more source

Enacting Digital Humanism in Education: A Comparative Case Study of Two Teachers in Greece and Australia

open access: yesFuture in Educational Research, EarlyView.
ABSTRACT The rapid expansion of digital technologies in education, accelerated by the COVID 19 pandemic, has transformed teaching and learning worldwide. Although digital humanism has emerged as an important framework for aligning technological development with human values, its enactment in educational practice remains underexplored.
Eunice Yin Yung Chiu
wiley   +1 more source

Medicated Optimism

open access: yesHealth Economics, EarlyView.
ABSTRACT Do people experiencing depression form accurate expectations about losing their jobs? Linking Estonian panel survey data to administrative employment, diagnosis, and prescription records, I track within‐person changes in expected job loss and subsequent realized job loss as individuals move into and out of depression and depression medication.
Penglong Li
wiley   +1 more source

Navigating Workplace Bullying: A Critical Theory Exploration of Lecturers' Experiences in a Higher Education Context

open access: yesHuman Resource Development Quarterly, EarlyView.
ABSTRACT Workplace bullying (WB) remains a pervasive concern across all sectors, including higher education institutions (HEIs), where shifting power dynamics, performance pressures, and transformation mandates often create fertile ground for systemic abuse.
Helen Meyer
wiley   +1 more source

Somatic cell reprogramming for Parkinson's disease treatment

open access: yesIbrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Posttraumatic stress disorder 2 months after induced vaginal delivery: A multicenter prospective study

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objectives An increased risk of postpartum posttraumatic stress disorder (PTSD) has been reported in women who had labor induced. Knowledge of childbirth‐related PTSD in this context remain poorly documented. Our aim was to assess the PTSD prevalence and identify characteristics associated with it after induced vaginal delivery at or near term.
Alizée Froeliger   +26 more
wiley   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

open access: yesiNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid   +4 more
wiley   +1 more source

Analysis of individualized brain–gut association networks and transcriptional patterns in major depressive disorder

open access: yesInterdisciplinary Medicine, EarlyView.
Individualized brain–gut association networks suggest potential neuropathological mechanisms in MDD and MDDSI. Multilevel brain–gut association changes involving HSV‐1 and inflammation may be relevant to MDD, whereas alterations related to insulin metabolism may play a potential role in the neuropathological mechanisms of MDDSI.
Wei Wang   +10 more
wiley   +1 more source

Assisted suicide [PDF]

open access: yes
this article looks at assisted suicide in the light of the UK government's suicide prevention ...
Matthews, Pia
core   +2 more sources

Reframing Clinical Supervision in Addiction Treatment: A Blended Developmental, Competency‐Based, and Trauma‐Informed Framework

open access: yesJournal of Addictions &Offender Counseling, EarlyView.
ABSTRACT This article examines the current landscape of clinical supervision in addiction treatment and proposes a blended supervision framework integrating developmental, competency‐based, and trauma‐informed approaches. The article explores how this integrated model can enhance clinical competence, ethical practice, and counselor resilience while ...
Cyrus Williams   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy