Results 41 to 50 of about 1,267,152 (310)

The Mind From Within: Visceral Roots of Human Cognition

Advanced Science, EarlyView.
The physiological activity of visceral organs, such as the heart, the lungs, and the gut, is surprisingly linked to many sophisticated mental operations, such as remembering the past, being aware of ourselves, making choices, and forging social bonds.
Alessandro Monti, Salvatore Maria Aglioti   +1 more
wiley   +1 more source

Community-Based Case Management for the Prevention of Suicide Reattempts in Kaohsiung, Taiwan

, 2014
Although a previous suicide attempt constitutes a major risk factor for an eventual completed suicide, few interventions specifically designed to prevent suicide reattempts have been evaluated.
李明濱, Chen, Wei-Jen;Chen, Cheng-Chung;Ho, Chi-Kung;Lee, Ming-Been;Lin, Guei-Ging;Chou, Frank Huang-Chih   +1 more
core   +1 more source

LRG1 Drives Pathological Angiogenesis by Disrupting Neutrophil Mitochondrial Homeostasis in Bladder Cancer

Advanced Science, EarlyView.
In bladder cancer, LRG1 binds to ANXA2 to trigger mitochondrial ROS‐dependent NETosis. This pathogenic cascade actively uncouples endothelial‐mural cell interactions, driving profound vascular destabilization. Consequently, targeting the LRG1‐ANXA2 axis attenuates the neutrophil burden and induces structural vascular normalization, offering a powerful ...
Dongshan Chen, Cong Zhang, Song Xue, Yuan Zeng, Haochen Cui, Chenfei Wang, Jiayi Feng, Lei Yan, Yuanwei Zang   +8 more
wiley   +1 more source

The ripple effect: understanding the exposure and impact of suicide in Australia [PDF]

, 2016
This research report undertaken by Suicide Prevention Australia and the University of New England is based on the responses of 3,220 Australian residents who self- identified as having been touched by suicide in some way.
Suicide Prevention Australia
core   +1 more source

Characteristics of adolescents who visit the emergency department following suicide attempts: comparison study between adolescents and adults

BMC Psychiatry, 2019
Background The purpose of this study was to identify the demographic and clinical characteristics of suicide attempts in adolescents who visit the emergency department compared to those of adults. Methods This study included 149 children under the age of
Jinhee Lee, Yeon Sik Bang, Seongho Min, Joung-Sook Ahn, Hyun Kim, Yong-Sung Cha, In-Suk Park, Min-Hyuk Kim   +7 more
doaj   +1 more source

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source

Epidemiologic Survey of Suicide Attempters Hospitalized in Hamadan Sina Hospital in 2001-2002

پزشکی بالینی ابن سینا, 2007
Introduction & Objective: Suicide is the most basic urgency of psychiatry and one of the greatest problems of human. Awareness of epidemiologic factors can help to predict it. The marital status, age, sex and socio-economical and geophysical factors such
Ali Ghaleiha, Fatemeh Behroozi Fard
doaj  

Management in primary care at the time of a suicide attempt and its impact on care post-suicide attempt: an observational study in the French GP sentinel surveillance system

BMC Family Practice, 2020
Background We aimed to describe primary care management at the time of a suicide attempt (SA) and after the SA. Methods An observational (cross-sectional) study was conducted among 166 sentinel GPs within France (a non-gatekeeping country) between 2013 ...
Nadia Younes, Mathieu Rivière, Frédéric Urbain, Romain Pons, Thomas Hanslik, Louise Rossignol, Christine Chan Chee, Thierry Blanchon   +7 more
doaj   +1 more source

Exploring the lived experiences of suicide attempt survivors [PDF]

, 2015
Suicide is a major problem in society and remains a challenge for services. Approaches to suicidality occur across individual, inter-personal and socio-cultural levels. However, the dominant narrative remains a biomedical one.
Redfern, C.
core  

Repurposing a Small Molecule Plant Hormone as a Tunable ON‐Switch for CAR‐T Cell Immunotherapy

Advanced Science, EarlyView.
By engineering a receptor system integrating the plant auxin receptor AFB1 with its co‐receptor IAA7, we enable ligand‐dependent interactions triggered by the plant hormone auxins. This design allows rapid, reversible, and dose‐dependent T cell activation, resulting in potent cytotoxicity against B‐cell lymphoma in vitro and in vivo.
Hongxiang Zeng, Lei Zheng, Rongkun Tao, Sirui Zheng, Yanke Zhong, Yongxia Niu, Peng Zhang, Xiang Ma, Chen Yang, Min Zhang, Fuyu Duan, Jing Yang, Xuan Wei, Xiang Zhou, Zhenbiao Yang, Zhaoxi Sun, Qizhou Lian   +16 more
wiley   +1 more source