Results 111 to 120 of about 349,298 (311)

A Systematic Review of Adverse Childhood Experiences and Epigenetic Age Acceleration in Later Adult Life Measured With Second and Third‐Generation Epigenetic Clocks

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT We examined the relationship between adverse childhood experiences (ACEs) and epigenetic age acceleration (EAA) in adulthood as measured by second and third generation epigenetic clocks by performing a systematic review of the literature. The electronic databases MEDLINE and EMBASE were searched on 17 July 2023.
Matthew Green   +2 more
wiley   +1 more source

Psychiatric and Cognitive Features in Italian Women With the FMR1 Premutation: A Comprehensive Assessment Using SCID‐5 and Standardized Cognitive Measures

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Women with the FMR1 premutation (PM) are at increased risk for fragile X‐associated conditions (FXPAC), including cognitive and psychiatric features collectively termed fragile X‐associated neuropsychiatric disorders (FXAND). This study is the first to systematically investigate cognitive and psychiatric features in Italian female premutation ...
Federica Alice Maria Montanaro   +5 more
wiley   +1 more source

Factors associated with recent suicide attempts among high-risk callers aged 12-25 to a suicide prevention hotline

open access: yesGuangxi Yike Daxue xuebao
Objective To compare the differences in demographic and socio-psychological factors between those with suicide plans and those with suicide attempts within two weeks among high-risk callers aged 12-25 to a suicide prevention hotline, and to explore ...
WU Jianlan, TONG Yongsheng
doaj   +1 more source

School Based Responses to Non-Suicidal Self Injury and Suicide: Literature Considerations When Framing a Policy Response [PDF]

open access: yes, 2019
Deliberate Non-Suicidal Self Injury (NSSI) and suicide present distinct but related concerns for schools. An Australian study of over 6,300 families containing children/ adolescents aged 4 to 17 years found that one in 10 young people had engaged with ...
O\u27Gorman, Shannon, Wiseman, Martin
core   +1 more source

Are There Causal Associations Between Obsessive‐Compulsive Disorder and Cardiometabolic Phenotypes? A Genetic Correlation and Bi‐Directional Mendelian Randomization Study

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT In epidemiological studies, obsessive‐compulsive disorder (OCD) is robustly associated with increased risk of cardiometabolic disorders, including cardiovascular diseases, type 2 diabetes, and obesity. However, the mechanisms behind these associations are unclear. We conducted genetic correlation analyses to explore shared genetic etiology and
Robyn E. Wootton   +217 more
wiley   +1 more source

From Covalent Traps to Fluorescent Beacons: The Expanding Arsenal of Chemical Probes for Studying Ubiquitin and Ubiquitin‐Like Proteins

open access: yesAngewandte Chemie, EarlyView.
A large variety of chemistry‐based ubiquitin probes have been developed. ABSTRACT Ubiquitin (Ub) and ubiquitin‐like proteins (Ubls) orchestrate diverse cellular processes through reversible post‐translational modification of target proteins. Their conjugation is governed by a cascade of E1 activating, E2 conjugating, and E3 ligating enzymes, while ...
Saibal Chanda, Wenshe Ray Liu
wiley   +2 more sources

Factors Related to Suicide Attempts by Poisoning in Iranian Children [PDF]

open access: yes
Objective: Suicide is a major health problem especially in children. Even a large proportion of healthy children have thought about suicide attempt. Some factors are suggested as risk factors for suicide attempt among children such as prior suicide ...
ثقه الاسلام, طاهره   +4 more
core  

Understanding Youth Assaults of Police Officers in Australia: A Power Threat Meaning Framework Analysis

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT This study explores youth violence towards police officers in Australia through the Power Threat Meaning Framework (PTMF) to better understand the underlying factors contributing to such violence; focusing on power dynamics, childhood adversity, and trauma.
Dimitra Lattas   +4 more
wiley   +1 more source

Suicide attempts: a contingency analysis

open access: yesEstudos de Psicologia (Campinas)
The aim of this study was to understand, from the perspective of behavioral analysis, the possible antecedents and consequences of a suicide attempt for the individual responsible, using reports from patients that were hospitalized in a psychiatric ...
Flávia Caroline Figel   +2 more
doaj   +1 more source

Age of First Suicide Attempt in Men and Women: An Admixture Analysis

open access: yesThe Scientific World Journal, 2012
Objectives. To define different subgroups of suicide attempters according to age at onset of suicide attempts. Methods. Participants were 229 suicide attempters (147 females; 82 males) admitted to a general hospital in Madrid, Spain.
Hilario Blasco-Fontecilla   +6 more
doaj   +1 more source

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