Results 91 to 100 of about 7,868,042 (360)

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

Advanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang, Gulizeba Aimaiti, Yuanye Guan, Yuzhe Sha, Wei Zhou, Jiefeng Shen, Bo Zhao, Wei‐En Yuan   +7 more
wiley   +1 more source

Cues and knowledge structures used by mental-health professionals when making risk assessments [PDF]

, 2008
Background: Research into mental-health risks has tended to focus on epidemiological approaches and to consider pieces of evidence in isolation. Less is known about the particular factors and their patterns of occurrence that influence clinicians’ risk ...
Ann Adams, Bouch J., Buckingham C. D, Buckingham C. D., Buzan T, Carter G., Castle K., Chris Mace, Christopher D. Buckingham, Dick P., Doctor R, Hanson R. K, Harris E. C., Higgins N., Holdsworth N., Maden A, Mays N., Monahan J., Morgan H. G., Morgan H. G., Muehlenkamp J. J, Neuendorf K, Owens D., Ryan T, Skegg K, Stengel E, Szmukler G, Watts D.   +27 more
core   +3 more sources

Suicide Risk in Obsessive-Compulsive Disorder and Exploration of Risk Factors: A Systematic Review

Current Neuropharmacology, 2019
Background Historically, OCD has been considered to be associated with a relatively low risk of suicide. Recent studies, on the contrary, revealed a significant association between OCD and suicide attempts and ideation.
U. Albert, D. De Ronchi, G. Maina, M. Pompili   +3 more
semanticscholar   +1 more source

Effectiveness of Pre‐Transplant Dual GLP‐1 Receptor Agonist and SGLT2 Inhibitor Therapy on All‐Cause Mortality in Organ Transplantation Candidates with Obesity and Type 2 Diabetes: a Target‐Trial Emulation

Advanced Science, EarlyView.
This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang, Min‐Yu Tsou, Pin‐Hung Li, Jo‐Ching Chen, Yen‐Liang Liu, Gideon Meyerowitz‐Katz, Tsung‐Hsun Tsai, Pen‐Hua Su   +7 more
wiley   +1 more source

Suicide in Scottish military veterans: a 30-year retrospective cohort study [PDF]

, 2017
Background: Although reassuring data on suicide risk in UK veterans of the 1982 Falklands conflict and 1991 Gulf conflict have been published, there have been few studies on long-term overall suicide risk in UK veterans.
Bergman, B.P., Mackay, D.F., Pell, J.P., Smith, D.J.   +3 more
core   +1 more source

Parasitic Plant–Host Interactions: Molecular Mechanisms and Agricultural Resistance Strategies

Advanced Science, EarlyView.
Parasitic plants devastate global agriculture through sophisticated molecular interactions with host crops. This review synthesizes current understanding of parasitic plant‐host interactions, from strigolactone‐mediated germination and haustorium formation to host defense mechanisms.
Jiayang Shi, Qi Xie, Feifei Yu
wiley   +1 more source

A survey of suicide risk among university students across three regions in Java, Indonesia

Jurnal Ners
Introduction: Suicide remains a significant global health and social problem, with Indonesia showing a lower suicide rate compared to other Asian countries.
Ninik Yunitri, Erna Rochmawati, Henny Dwi Susanti, Nuraenah Nuraenah, Fitrian Rayasari, Dea Chairunnisa, Sephia Salsabila, Rani Septiawantari, Slametiningsih Slametiningsih   +8 more
doaj   +1 more source

Health Care for Veterans: Suicide Prevention [PDF]

, 2016
[Excerpt] Congress has attempted to address the problem of suicide among veterans through legislation and oversight hearings, both on prevention of veteran suicide specifically and on veteran mental health more broadly.
Bagalman, Erin
core   +3 more sources

Suicide Risk in Bipolar Disorder: A Brief Review

Medicina, 2019
Bipolar disorders (BDs) are prevalent mental health illnesses that affect about 1–5% of the total population, have a chronic course and are associated with a markedly elevated premature mortality. One of the contributors for the decreased life expectancy
P. Dome, Z. Rihmer, X. Gonda
semanticscholar   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source