Results 161 to 170 of about 7,868,042 (360)

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Metabolic syndrome increases the risk of suicide attempt: evidence from a population-based cohort and genomic analysis

Translational Psychiatry
Suicide is a critical global public health issue, where traditional risk assessment tools have limited predictive value, warranting the identification of novel risk assessment factors. Metabolic syndrome (MetS) has been linked to poor cognition and brain
Zhengyang Zhao, Min Xie, Shiwan Tao, Qiuyue Lv, Jiashuo Zhang, Jia Cai, Yunjia Liu, Yunqi Huang, Siyi Liu, Yulu Wu, Qiang Wang   +10 more
doaj   +1 more source

Safety, tolerability and pharmacokinetics of DNDI‐6148, a novel agent for leishmaniasis: A randomized, controlled, single ascending dose study in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aim The benzoxaborole derivative DNDI‐6148 is an antiparasitic agent with activity against multiple Leishmania protozoan species, including L. infantum and L. donovani, which cause visceral leishmaniasis. We investigated the safety, tolerability and pharmacokinetics of single oral doses of DNDI‐6148 in a randomized, parallel‐group, placebo‐controlled ...
Jean‐Yves Gillon, Sophie Delhomme, Delphine Launay, Séverine Blesson, Stéphanie Braillard, Pegah Maghdooni, Frauke Assmus, Richard Hoglund, Joel Tarning, Sabrina Loyau, Byron Arana, Mathilde Latreille‐Barbier, Yves Donazzolo   +12 more
wiley   +1 more source

Drug poisonings following bariatric surgery: Case series report

British Journal of Clinical Pharmacology, EarlyView.
Bariatric surgery alters gastrointestinal anatomy and physiology, which likely impacts upon oral medication absorption. Drug‐ and alcohol‐related deaths in this population are being increasingly reported; however, toxicological detail is lacking. Using data reported to the National Programme on Substance Use Mortality, we identified 18 deaths in people
Eman Mshari, Fannie LaJeunesse‐Trempe, Stephen Morley, Caroline Copeland   +3 more
wiley   +1 more source

Suicide risk and prevention during the COVID-19 pandemic

Lancet psychiatry, 2020
D. Gunnell, Louis Appleby, Ella Arensman, Keith Hawton, Ann John, Nav Kapur, Murad Khan, R. O’Connor, Jane Pirkis, Louis Ella Eric D Lai Fong Shu-Sen Ying-Yeh Helen Rakhi Appleby Arensman Caine Chan Chang Chen Christensen, Louis Appleby, Ella Arensman, E. Caine, L. Chan, Shu-Sen Chang, Ying-Yeh Chen, H. Christensen, R. Dandona, M. Eddleston, A. Erlangsen, D. Gunnell, J. Harkavy-Friedman, Keith Hawton, Ann John, Nav Kapur, Murad Khan, Olivia J. Kirtley, D. Knipe, F. Konradsen, Shiwei Liu, S. McManus, L. Mehlum, Matthew Miller, P. Moran, Jacqui Morrissey, C. Moutier, T. Niederkrotenthaler, M. Nordentoft, R. O’Connor, S. O’neill, A. Page, M. Phillips, Jane Pirkis, Steven I. Platt, M. Pompili, P. Qin, M. Rezaeian, M. Silverman, M. Sinyor, S. Stack, E. Townsend, G. Turecki, L. Vijayakumar, P. Yip   +53 more
semanticscholar   +1 more source

Listening to Hong Kong children's perspectives through pretend play

British Educational Research Journal, EarlyView.
Abstract Quality in early childhood education and care (ECEC) has become an increasing concern in recent years. The issue has been regularly discussed by different stakeholders. However, the rising concern regarding quality in ECEC has not seriously taken into account children's perspectives.
Suzannie K. Y. Leung
wiley   +1 more source

Suicide in Bangladesh: An Ecological Systems Analysis

Brain and Behavior
Background Suicide happens due to a complex interaction among multiple factors. Hence, prevention strategies should consider a wider range of personal and ecological aspects.
S. M. Yasir Arafat, Tamkeen Saleem
doaj   +1 more source

Needs Assessment of Suicide Prevention in Vermont Middle and High Schools [PDF]

, 2018
Introduction. Adolescent suicide is epidemic. 17% of high school students con- sidered suicide and 8% attempting to take their lives in 2015 nationwide.
Chawla, Rajan, Earle, William, Fontaine, Kristin, Goldberg, Eli, Griffin, Mary, Jemison, Jill, Kardys, Amanda, Moring, Nikolas, Schoen, Elias, Vayda, Emily   +9 more
core   +1 more source

The absent presence of disability in British higher education

British Educational Research Journal, EarlyView.
Abstract Rates of disability disclosure are steadily increasing in British higher education (HE), with 18% of the student population having a known disability in 2023/24. It might be assumed that progress is being made with increased representation, rights and support for disabled students.
G. Koutsouris, L. Stentiford, E. Dimitrellou, Z. Yu, Pujaningsih, N. Azizah   +5 more
wiley   +1 more source

Early evolutionary history of the seed

Biological Reviews, EarlyView.
ABSTRACT The seed is an essential stage in the life history of gymnospermous and angiospermous plants, facilitating both their survival and dispersal. We reappraise knowledge of the evolutionary history of the gymnospermous seed, from its origin in the late Devonian through to the well‐known end‐Permian extinctions – an interval encompassing the ...
Richard M. Bateman, Alan R. T. Spencer, Jason Hilton   +2 more
wiley   +1 more source