Results 81 to 90 of about 7,868,042 (360)

Prediction of Sex-Specific Suicide Risk Using Machine Learning and Single-Payer Health Care Registry Data From Denmark.

open access: yesJAMA psychiatry, 2019
Importance Suicide is a public health problem, with multiple causes that are poorly understood. The increased focus on combining health care data with machine-learning approaches in psychiatry may help advance the understanding of suicide risk ...
J. Gradus   +7 more
semanticscholar   +1 more source

Amodiaquine Enhances Anti‐Melanoma Efficacy of Attenuated Salmonella via Targeting Glutathione Reductase in Neutrophils

open access: yesAdvanced Science, EarlyView.
This study shows that Salmonella VNP20009 recruits pro‐tumor neutrophils that reduce its anticancer efficacy. Combining VNP with amodiaquine selectively eliminates these neutrophils by targeting glutathione reductase. A GR‐shRNA‐loaded VNP strain was further developed, demonstrating an innovative strategy integrating drug repurposing with synthetic ...
Wanfa Dong   +13 more
wiley   +1 more source

Creating a Chinese suicide dictionary for identifying suicide risk on social media [PDF]

open access: yesPeerJ, 2015
Introduction. Suicide has become a serious worldwide epidemic. Early detection of individual suicide risk in population is important for reducing suicide rates.
Meizhen Lv   +3 more
doaj   +2 more sources

Genetic risk, parental history, and suicide attempts in a diverse sample of US adolescents

open access: yesFrontiers in Psychiatry, 2022
BackgroundAdolescent suicide is a major health problem in the US marked by a recent increase in risk of suicidal behavior among Black/African American youth.
Ran Barzilay   +12 more
doaj   +1 more source

Enhancing suicide risk assessment through the use of visual metaphor : a thesis presented in partial fulfillment of the requirements for the degree of Master of Health Science in Psychology at Massey University, Albany Campus, New Zealand [PDF]

open access: yes, 2016
Competent assessment and management of the risk of harm is a core competency that mental health professionals are expected to possess. However, despite this expectation, adequate training programs have been lacking for decades and, even when risk ...
Alyami, Mohsen Mohammed M
core  

Suicide Risk and Protective Factors: A Network Approach

open access: yesArchives of Suicide Research, 2020
Objective Suicide is a complex phenomenon, with numerous factors contributing to an individual’s risk of suicide. The aim of the present study was to explore how risk and protective factors for suicide interact with one another in a network sense and to ...
Mikayla S Holman, Matt N. Williams
semanticscholar   +1 more source

A Glucose‐Responsive Intelligent Antibacterial and Oxygen‐Producing Hydrogel Promotes the Healing of Diabetic Wounds by Regulating Cellular Heterogeneity

open access: yesAdvanced Science, EarlyView.
We have developed a glucose‐triggered on‐demand drug delivery CF‐CPGaMPN hydrogel based on borate ester bonds. It inactivates microbes, releases oxygen, and enables on‐demand drug release in high‐glucose environments to promote healing of diabetic wounds. Single‐cell sequencing reveals that the CF‐CPGaMPN hydrogel significantly alleviates dysfunctional
Manxuan Liu   +8 more
wiley   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

open access: yesAdvanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu   +11 more
wiley   +1 more source

Developmental trajectories of suicide risk in college students: a three-year Latent Growth Mixed Model study

open access: yesFrontiers in Psychology
BackgroundThis study aimed to explore the developmental trajectories of suicide risk among college students and examine the influence of demographic, psychological, and social factors on these trajectories.MethodsA three-year follow-up study was ...
Liu Zhuojun   +3 more
doaj   +1 more source

Natural Language Processing of Social Media as Screening for Suicide Risk

open access: yesBiomedical Informatics Insights, 2018
Suicide is among the 10 most common causes of death, as assessed by the World Health Organization. For every death by suicide, an estimated 138 people’s lives are meaningfully affected, and almost any other statistic around suicide deaths is equally ...
Glen A. Coppersmith   +3 more
semanticscholar   +1 more source

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