Results 51 to 60 of about 364,799 (215)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Assessing land suitability for crop diversification in Cambodia [PDF]
, 2005 Opportunities for poverty alleviation in Cambodian agriculture are emerging in diversification from traditional wet season lowland rice (Oryza sativa) production to double-cropped, rice-based production systems and to upland cropping.
Vance, W. +4 more
core
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Бонитетна оценка на Техногенни почви. Част III. Пригодност за отглеждане на фуражни култури
Почвознание, агрохимия и екология, 2012 This article is а natural continuation оf studies aimed аt evaluating the suitability of Technosols reclaimed with humus layer for agriculture. The studied soils (mine spoils) are deep and not differentiated with loam оr clay loam texture.
ВЕНЕРА ЦОЛОВА +3 more
doaj
, 2023 This study analyses mandatory suitability and affordability assessment embodied in the Guidelines on Responsible Financing issued by the Central Bank of Malaysia, focusing on conventional banks, Islamic banks and prescribed development financial ...
Ilias, Ibtisam @ Ilyana +3 more
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Téoros, 2008 While assessments of tourism attractions are among the fundamentals of tourism planning, they are the “poor cousins” of accessibility, transportation, and accommodations analysis (Pearce, 1991).
Nick Novakowski +2 more
doaj
Assessing beach tourism suitability to support sustainable tourism development on Untung Jawa Island [PDF]
BIO Web of ConferencesUntung Jawa Island is one of the most visited tourist destinations in the Thousand Islands of Jakarta. This status of a tourist area must be developed in a directed manner by evaluating the level of suitability of the coastal environment to support ...
Yasri Dzamir Alfath +7 more
doaj +1 more source
The Perils of Ignoring Data Suitability: The Suitability of Data Used to Train Neural Networks Deserves More Attention [PDF]
, 2011 The quality and quantity (we call it suitability from now on) of data that are used for a machine learning task are as important as the capability of the machine learning algorithm itself.
Swingler, Kevin
core