Results 91 to 100 of about 164,018 (269)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Population Flow-Based Evaluation and Zoning Optimization for Rural Settlement Utilization Efficiency in Metropolitan Suburbs

open access: yesLand
To address the utilization challenges of rural settlements in metropolitan suburbs, this study takes the suburban areas of Wuhan as its research object.
Jiancong Xiang   +3 more
doaj   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Structural-Functional Suitability Assessment of Yangtze River Waterfront in the Yichang Section: A Three-Zone Spatial and POI-Based Approach

open access: yesLand
The Yangtze River Economic Belt is a crucial driver of China’s economy, and its shoreline is a strategic, finite resource vital for ecological security, flood control, navigation, and socioeconomic development. However, intensive development has resulted
Xiaofen Li   +5 more
doaj   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Spatial Suitability Evaluation and Potential Emission Reduction Benefit Prediction of Photovoltaic Land in Guangdong Province

open access: yesRedai dili
Driven by the “double carbon” goal, photovoltaic power generation has become a key pathway for the low-carbon transformation of energy. Focusing on Guangdong Province, a major energy-consuming region, this study constructs a multi-system coordinated ...
Zhuoyi Zhou   +5 more
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

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