Results 91 to 100 of about 2,121,257 (344)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Greater Boston Youth Symphony Orchestras: Repertory Orchestra and String Training Ensemble Winter Concert, January 29, 1984 [PDF]

open access: yes, 1984
This is the concert program of the Greater Boston Youth Symphony Orchestras: Repertory Orchestra and String Training Ensemble performance on Sunday, January 29, 1984 at 8:00 p.m., at the Concert Hall, 855 Commonwealth Avenue.
School of Music, Boston University
core  

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Boston University All-Campus Orchestra, December 9, 2010 [PDF]

open access: yes, 2010
This is the concert program of the Boston University All-Campus Orchestra performance on Thursday, December 9, 2010 at 8:00 p.m., at the Boston University Concert Hall, 855 Commonwealth Avenue, Boston, Massachusetts.
School of Music, Boston University
core  

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Automatic Repair of Real Bugs: An Experience Report on the Defects4J Dataset

open access: yes, 2015
Defects4J is a large, peer-reviewed, structured dataset of real-world Java bugs. Each bug in Defects4J is provided with a test suite and at least one failing test case that triggers the bug.
Durieux, Thomas   +4 more
core   +1 more source

A First-Order Logic Formalization of the Industrial Ontology Foundry Signature Using Basic Formal Ontology [PDF]

open access: yes, 2019
Basic Formal Ontology (BFO) is a top-level ontology used in hundreds of active projects in scientific and other domains. BFO has been selected to serve as top-level ontology in the Industrial Ontologies Foundry (IOF), an initiative to create a suite of ...
Ameri, Farhad   +6 more
core  

A Model to Estimate First-Order Mutation Coverage from Higher-Order Mutation Coverage

open access: yes, 2016
The test suite is essential for fault detection during software development. First-order mutation coverage is an accurate metric to quantify the quality of the test suite. However, it is computationally expensive.
Demeyer, Serge   +2 more
core   +1 more source

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