Results 111 to 120 of about 480,719 (323)

Multiplex single‐cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer

Molecular Oncology, EarlyView.
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien, Marta E. Hjelmeland, Hege F. Berg, Rose M. Gold, Kathrine Woie, Lars A. Akslen, Ingfrid S. Haldorsen, Camilla Krakstad   +7 more
wiley   +1 more source

Pioneering protein degradation for agricultural applications

Communications Biology
As the world of agrochemicals is entering a race for efficient and safe modalities, there is an urgent and specific need for entirely new modes of action. Proteolysis-targeting chimeras (PROTACs) recruit naturally occurring E3 ubiquitin ligases to induce
Gina L. Morgan, Hamilton Dickson, Breanna Ford, Aleksandra Noras, Steven C. Bremmer, Brian E. Watts, Joseph Pilotte, Ed Anderson, Eric D. Sullivan, Mikayla Stoner, Daniel Ouedraogo, Daniel J. Saltzberg, Karunakar R. Pothula, Paul Ingram, John Catalano, Melina Lillich, Carl-Christian Kolbe, Anne Pfeiffer, Christopher C. Ladner, Sam Gattis, Jason Speake, Stephanie Voss, Kelly Broccio, Denis Fourches   +23 more
doaj   +1 more source

Bone marrow aspirate concentrate for the treatment of osteochondral lesions of the talus: a systematic review of outcomes

Journal of Experimental Orthopaedics, 2016
Background The goal of this perform a systematic review on the outcomes of bone marrow aspirate concentrate (BMAC) for the treatment of chondral defects and osteoarthritis (OA) of the talus.
Jorge Chahla, Mark E. Cinque, Jason M. Schon, Daniel J. Liechti, Lauren M. Matheny, Robert F. LaPrade, Thomas O. Clanton   +6 more
doaj   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Unbiased interrogation of memory B cells from convalescent COVID-19 patients reveals a broad antiviral humoral response targeting SARS-CoV-2 antigens beyond the spike protein

Vaccine: X, 2021
Patients who recover from SARS-CoV-2 infections produce antibodies and antigen-specific T cells against multiple viral proteins. Here, an unbiased interrogation of the anti-viral memory B cell repertoire of convalescent patients has been performed by ...
Jillian M. DiMuzio, Baron C. Heimbach, Raymond J. Howanski, John P. Dowling, Nirja B. Patel, Noeleya Henriquez, Chris Nicolescu, Mitchell Nath, Antonio Polley, Jamie L. Bingaman, Todd Smith, Benjamin C. Harman, Matthew K. Robinson, Michael J. Morin, Pavel A. Nikitin   +14 more
doaj  

Étude théorique et expérimentale des coups de bélier (Suite.) [PDF]

, 1917
Charles Camichel, Denis Eydoux, Maurice Gariel   +2 more
openalex   +1 more source

Le Ricin (Suite).

Revue de botanique appliquée et d'agriculture coloniale, 1930
Trochain Jean. Le Ricin (Suite).. In: Revue de botanique appliquee et d'agriculture coloniale, 10ᵉ annee, bulletin n°108, aout 1930. pp. 671-675.
openaire   +4 more sources

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

Molecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren, Kathryn A. Wierenga, Frank M. Riemers, Elsbeth A. van Liere, Bart Westendorp   +4 more
wiley   +1 more source

SUITE BRITEL [PDF]

, 2018
La información, ese bien que influencia tiene en el mundo moderno por su capacidad de provocar cambios en quién la recibe, alcanza su máximo exponente cuando se produce su difusión. Uno de los canales más importantes de difusión y transmisión de la información es la TV, que utiliza diferentes medios de transmisión (telecomunicaciones) para hacer llegar
openaire   +1 more source

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

Molecular Oncology, EarlyView.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan, Fenghua Tan, Jie Wu, Zhaoyang Zeng, Wenjia Guo, He Huang, Wei Xiong   +6 more
wiley   +1 more source