Results 51 to 60 of about 2,015,869 (349)

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

open access: yesFEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki   +4 more
wiley   +1 more source

Unbiased interrogation of memory B cells from convalescent COVID-19 patients reveals a broad antiviral humoral response targeting SARS-CoV-2 antigens beyond the spike protein

open access: yesVaccine: X, 2021
Patients who recover from SARS-CoV-2 infections produce antibodies and antigen-specific T cells against multiple viral proteins. Here, an unbiased interrogation of the anti-viral memory B cell repertoire of convalescent patients has been performed by ...
Jillian M. DiMuzio   +14 more
doaj   +1 more source

Assistant Suite [PDF]

open access: yes, 2017
This project was conducted to demonstrate a voice-to-mechanical application from one source to multiple platforms with the use of hardware-to-software technology.
Greene, Dale, Nag, Ritvik, Pham, John
core   +1 more source

An Ontological Approach to Representing the Product Life Cycle [PDF]

open access: yes, 2019
The ability to access and share data is key to optimizing and streamlining any industrial production process. Unfortunately, the manufacturing industry is stymied by a lack of interoperability among the systems by which data are produced and managed, and
Ali, Munira Mohd   +7 more
core   +1 more source

ACSS2 involved in acetyl‐CoA synthesis regulates skeletal muscle function

open access: yesFEBS Letters, EarlyView.
The enzyme acyl‐coenzyme A synthetase short‐chain family member‐2 (ACSS2) catalyzes the conversion of acetate to acetyl‐CoA, but its function in skeletal muscle is unclear. We studied ACSS2 deficiency in mouse and fly models. Skeletal muscle from the mouse model showed atrophic fibers, excess lipid, and depleted NADH.
Mekala Gunasekaran   +6 more
wiley   +1 more source

« Quelque chose, tout de suite ! »

open access: yesCahiers d’histoire, 2017
La défense de l’Exposition de 1937 fut l’une des batailles menées par le Parti communiste français de juillet 1936 à janvier 1938. Paul Vaillant-Couturier, Parisien enraciné dans la banlieue de Paris et interlocuteur des intellectuels depuis 1932, y joue
Annie Burger-Roussennac
doaj   +1 more source

Boston University Early Music Series: Tamara Loring, harpsichord, April 10, 1987 [PDF]

open access: yes, 1987
This is the concert program of the Boston University Early Music Series: Tamara Loring, harpsichord performance on Friday, April 10, 1987 at 8:00 p.m., at the Marshall Room, 855 Commonwealth Avenue. Works performed were Pavane, F# minor by Louis Couperin,
School of Music, Boston University
core  

Automatic Repair of Buggy If Conditions and Missing Preconditions with SMT [PDF]

open access: yes, 2014
We present Nopol, an approach for automatically repairing buggy if conditions and missing preconditions. As input, it takes a program and a test suite which contains passing test cases modeling the expected behavior of the program and at least one ...
Berre, Daniel Le   +3 more
core   +4 more sources

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

open access: yesFEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke   +2 more
wiley   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

open access: yesFEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer   +10 more
wiley   +1 more source

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