Results 71 to 80 of about 2,121,257 (344)

The MEME Suite [PDF]

open access: yesNucleic Acids Research, 2015
The MEME Suite is a powerful, integrated set of web-based tools for studying sequence motifs in proteins, DNA and RNA. Such motifs encode many biological functions, and their detection and characterization is important in the study of molecular interactions in the cell, including the regulation of gene expression.
Bailey, Timothy L.   +3 more
openaire   +3 more sources

An Ontological Approach to Representing the Product Life Cycle [PDF]

open access: yes, 2019
The ability to access and share data is key to optimizing and streamlining any industrial production process. Unfortunately, the manufacturing industry is stymied by a lack of interoperability among the systems by which data are produced and managed, and
Ali, Munira Mohd   +7 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Self-consistent simulation of plasma scenarios for ITER using a combination of 1.5D transport codes and free-boundary equilibrium codes

open access: yes, 2013
Self-consistent transport simulation of ITER scenarios is a very important tool for the exploration of the operational space and for scenario optimisation.
Albanese, R   +22 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

<b>Suite Meridiana / Southern Suite</b> // Suite meridiana / Suite sureña

open access: yesEcozon@: European Journal of Literature, Culture and Environment, 2013
Abstract This is a collection of photos taken during my explorations--both as a sailor and as a mountain biker--of the Mediterranean presences in Southern Italy. These presences include elemental instability, natural-cultural metamorphoses, and silences.
openaire   +2 more sources

Man Shu, piano, April 16, 2015 [PDF]

open access: yes, 2015
This is the concert program of the Man Shu, piano performance on Thursday, April 16, 2015 at 4:00 p.m., at the Concert Hall, 855 Commonwealth Avenue. Works performed wee English Suite in G minor, BWV 808 by Johann Sebastian Bach, Piano Sonata NO. 18, Op.
School of Music, Boston University
core  

Home - About - Disclaimer - Privacy