Results 81 to 90 of about 2,015,869 (349)

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Boston University All-Campus Orchestra, December 9, 2010 [PDF]

open access: yes, 2010
This is the concert program of the Boston University All-Campus Orchestra performance on Thursday, December 9, 2010 at 8:00 p.m., at the Boston University Concert Hall, 855 Commonwealth Avenue, Boston, Massachusetts.
School of Music, Boston University
core  

Apologetica (suite)

open access: yesRevue des Sciences Religieuses, 1994
Les divergences doctrinales relevées entre L et DR sont illusoires. Les unes résultent d'une mauvaise interprétation du texte (les modalités de la résurrection, le Dieu potier, le jugement porté sur les valeurs terrestres), les autres apparaissent au sein d'un même ouvrage témoignant des contradictions inhérentes à toute pensée non systématisée (par ex.
openaire   +3 more sources

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

Piccola Suite Fluviale

open access: yesCuadernos de Filología Italiana, 2004
Poemas inéditos de Giovanni ...
Giovanni Raboni
doaj  

TLS clients testing

open access: yesТруды Института системного программирования РАН, 2018
The paper presents a model-based approach to conformance testing of TLS implementations. It discusses the formal model of TLS protocol, the structure of the test suite. JavaTesK tool, based on UniTESK technology, was used to develop the test suite. A set
A. V. Nikeshin   +2 more
doaj   +1 more source

SPECIES HEPATICARUM (suite)

open access: yes, 1908
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +6 more sources

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Greater Boston Youth Symphony Orchestras: Repertory Orchestra and String Training Ensemble Winter Concert, January 29, 1984 [PDF]

open access: yes, 1984
This is the concert program of the Greater Boston Youth Symphony Orchestras: Repertory Orchestra and String Training Ensemble performance on Sunday, January 29, 1984 at 8:00 p.m., at the Concert Hall, 855 Commonwealth Avenue.
School of Music, Boston University
core  

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