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Metachromatic Leukodystrophy (Sulfatase A Deficiency) and Multiple Sulfatase Deficiency

1975
Metachromatic leukodystrophy was first described in adults. Alzheimer (1910) gave a brief abstract of a case which he characterized as a white matter disease with destruction of myelin and abundant, brightly metachromatic deposits in glia cells. Witte (1921) reported similar findings and recognized the accumulation of metachromatic granules in neuronal
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Sulfatase inhibitors: a patent review

Expert Opinion on Therapeutic Patents, 2012
Steroid sulfatase (STS) converts sulfated hormones to free hormones of importance in hormone-dependent diseases such as breast cancer and endometriosis. Carbohydrate sulfatases degrade complex carbohydrates as part of normal cellular turnover; certain lysosomal storage disorders (LSDs) involve defective processing of sulfated glycosaminoglycans by ...
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The common identity of UDP-N-acetylgalactosamine 4-sulfatase, nitrocatechol sulfatase (arylsulfatase), and chondroitin 4-sulfatase.

Biochimica et biophysica acta, 1980
Evidence is presented indicating that three sulfatase activities towards UDP-N-acetylgalactosamine 4-sulfate, nitrocatechol sulfate, and chondroitin 4-sulfate are functions of the same hen oviduct enzyme. Using chondroitin [35S]sulfate from chick embryo cartilage, it is shown that hydrolysis of ester sulfate by this enzyme is limited to 4-sulfate ...
M, Tsuji   +4 more
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Functions of duplicated glucosinolate sulfatases in the development and host adaptation of Plutella xylostella

Insect Biochemistry and Molecular Biology, 2020
Wei  Chen   +2 more
exaly  

Sulfatases: Structure, Mechanism, Biological Activity, Inhibition, and Synthetic Utility

Angewandte Chemie - International Edition, 2004
Sarah R Hanson   +2 more
exaly  

Microbial Sulfatases

Moscow University Chemistry Bulletin, 2018
S. V. Shvetsova, A. A. Kulminskaya
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Biology and function of the reversible sulfation pathway catalysed by human sulfotransferases and sulfatases

Chemico-Biological Interactions, 1998
Michael W H Coughtrie   +2 more
exaly  

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