Results 111 to 120 of about 589,999 (404)

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Chemical composition of ambient aerosol, ice residues and cloud droplet residues in mixed-phase clouds: single particle analysis during the Cloud and Aerosol Characterization Experiment (CLACE 6) [PDF]

, 2009
Two different single particle mass spectrometers were operated in parallel at the Swiss High Alpine Research Station Jungfraujoch (JFJ, 3580 m a.s.l.) during the Cloud and Aerosol Characterization Experiment (CLACE 6) in February and March 2007.
Borrmann, Stephan, Curtius, Joachim, Cziczo, Daniel J., Drewnick, Frank, Ettner-Mahl, Matthias, Kamphus, Michael, Keller, Livia, Klimach, Thomas, Mertes, Stephan   +8 more
core   +3 more sources

Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics

Advanced Biology, EarlyView.
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim, Kanghoon Choi, Amy Lin, Jungkyu Kim   +3 more
wiley   +1 more source

Investigating the Cellular Effects of GALC Dosing in Enzyme Replacement Therapy for Krabbe Disease Supports the Role of Nanomedicine

Advanced Biology, EarlyView.
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso, Sara Carpi, Laura Colagiorgio, Miriam De Sarlo, Mariacristina Gagliardi, Marco Cecchini   +5 more
wiley   +1 more source

Ferric sulfates on Mars: A combined mission data analysis of salty soils at Gusev crater and laboratory experimental investigations

, 2011
[1] A temporal visible near-infrared (VIS-NIR) spectral variation was observed from Tyrone yellowish salty soils based on seven periodic Pancam 13 filter observations made by the Spirit rover. The major change was the reduction of spectral slope from 434
Alian Wang, Z. Ling
semanticscholar   +1 more source

Consolidate Overview of Ribonucleic Acid Molecular Dynamics: From Molecular Movements to Material Innovations

Advanced Engineering Materials, EarlyView.
Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
wiley   +1 more source

ALTERACIÓN QUÍMICA DE LA SOLUCIÓN DE UN SUELO SULFATADO ÁCIDO, CON ENCALAMIENTO Y LAVADO EN COLUMNA DISTURBADAS ALTERATION OF ACID SULPHATE SOIL SOLUTION CHEMISTRY WITH LIMING AND WASHING IN DISTURBED COLUMNS

Revista U.D.C.A Actualidad & Divulgación Científica, 2009
La acidez de los suelos es uno de los principales factores que limitan la producción de los suelos sulfatados ácidos tropicales, siendo lenta la corrección con cal agrícola y lavado.
Enrique Combatt Caballero, Teobaldis Mercado Fernández, Graciliano Palencia Severiche   +2 more
doaj  

Effect of the Addition of Manganese Dioxide Nanoparticles on the Mechanical Properties of Concrete against Carbonation and Sulfate Attack

Buildings
This study evaluates the impact of the addition of nanoparticles of anodic manganese dioxide (NAMD) on the mechanical properties and resistance to chemical attack of concrete.
Ana Torre, Luisa Shuan, Noemi Quintana, Isabel Moromi, Jesus Basurto, Luis Mosquera, Noe Cortez   +6 more
doaj   +1 more source

Reactivity of aluminum sulfate and silica in molten alkalimetal sulfates in order to prepare mullite [PDF]

, 2004
With the aim of preparing mullite, reactions between aluminum sulfate and silica in appropriate proportions and molten sulfate media M2SO4 (M=Na and/or K) were performed at different temperatures.
Durand, Bernard, El Ouatib, Rachida, Er-Rakho, Lahcen, Guillemet-Fritsch, Sophie, Moussab, Redouane, Samdi, Azzeddine   +5 more
core   +1 more source

Comparative Study of Experimental Methods for Measuring Thermal Properties of 100Cr6 Steel Powders

Advanced Engineering Materials, EarlyView.
This study investigates the thermal properties of 100Cr6 steel in both bulk and powder forms. Measuring the very low thermal conductivity typically exhibited by powders poses significant challenges. To address this, two novel measurement techniques—temperature gradient and finite laser pulse response—are introduced and evaluated by comparison with the ...
Junsheng Zhuo, Hagen P. Kohl, Dongmei Liu, Lisa Matthäus, Arne Bochmann, Aaron Berger, Sebastian Weber, Stefan Nolte, Stephanie Lippmann   +8 more
wiley   +1 more source