Results 41 to 50 of about 89,086 (264)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Sulfate-reducing bacteria of the human intestine. II. The role in the diseases development
The modern literature data about the role of microflora in the diseases of the large intestine of man are summarized. Special attention is paid to the sulfate-reducing bacteria role in ulcerative colitis development. The basic ways of hydrogen metabolism
I. V. Kushkevych
doaj +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Uranyl Sulfate Nanotubules Templated by N-phenylglycine
The synthesis, structure, and infrared spectroscopy properties of the new organically templated uranyl sulfate Na(phgH+)7[(UO2)6(SO4)10](H2O)3.5 (1), obtained at room temperature by evaporation from aqueous solution, are reported.
Oleg I. Siidra +6 more
doaj +1 more source
ACE-ASIA - Regional climatic and atmospheric chemical effects of Asian dust and pollution [PDF]
Although continental-scale plumes of Asian dust and pollution reduce the amount of solar radiation reaching the earth's surface and perturb the chemistry of the atmosphere, our ability to quantify these effects has been limited by a lack of critical ...
Andrew M. Vogelmann +25 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Magmatic Intrusions into the Sulfur-Rich Carmel Formation on the Colorado Plateau, USA: Implications for the Mars 2020 Mission [PDF]
We report on basaltic dikes in the Colorado Plateau, which crosscut sulfate bearing sediments and compare this to Martian basalts and basaltic sediments in contact with sulfate ...
Crandall, J. R. +3 more
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Mechanisms for the creation of intrinsic electron-hole trapping centers in a CaSO4 crystall
The mechanism of creation of electron-hole trapping centers in CaSO4 at 15-300 K was investigated by the methods of vacuum-ultraviolet and thermoactivation spectroscopy. It is shown that electron-hole trapping centers are formed upon trap of electrons in
T.N. Nurakhmetov +7 more
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

