Results 41 to 50 of about 1,697 (218)
Геохімія техногенезу, 2021 The article presents the physical and geographical characteristics of the Synychan water intake section of the Izium water intake, which is located 8 km southeast of the city of Izium, Kharkiv region.
I. Udalov,, D. Piatash
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Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
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Veterinary Sciences, 2022 High concentrations of total dissolved solids (TDS) in water have been reported to increase the incidence of diarrhea and reduce nursery pig growth performance.
Ryan Samuel
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
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BALKAN YARIMADASI'NDA JEOLOJİK ZAMAN BOYUNCA SÜLFÜR
Bulletin of the Mineral Research and Exploration, 2002 Uzun bir dönemdir yürütülmekte olan araştırmalarda Balkan Yarımadasındaki en yaşlı metalojenik evrelerin, ana kimyasal elementlerden biri olan sülfürü içeren oluşukları sınırlı sayıda kapsadığı belirlenmiştir. Bu nedenle de.
Radule POPOVİC
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Frontiers in Microbiology, 2019 The hypersaline sediment and groundwater of playa lake, Lake Lucero, at the White Sands National Monument in New Mexico were examined for microbial community composition, geochemical gradients, and mineralogy during the dry season along a meter and a ...
Mihaela Glamoclija +6 more
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Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
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Geochemical approach in assessing the technogenic impact on soils
Записки Горного института, 2020 The soil assessment was carried out in the technogenically-affected area of Irkutsk Oblast with the geochemical approach as a key geoecological method using physical and chemical techniques of analysis and ecodiagnostics.
Galina I. Sarapulova
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