Results 141 to 150 of about 212,000 (313)

Natural Products Inspired Scaffold Diversification Leads to Unnatural Molecular Warhead and Covalent Strategy to Modulating Protein Function through Electrophilic Bromine Transfer

open access: yesAdvanced Science, EarlyView.
We report a new thiolate‐reactive α,α‐gem‐dibromo lactam warhead that activates transcription factor Nrf2 and demonstrates anti‐inflammatory activities, which have implications in cancer, neurodegeneration, and cardiovascular diseases. RNA‐seq illuminated detailed transcriptional profiles, and chemical reactions with cysteine‐containing compounds ...
Beau R. Brummel   +16 more
wiley   +1 more source

Formation of multi-shelled nickel-based sulfide hollow spheres for rechargeable alkaline batteries

open access: yes, 2018
Metal sulfides with multi-shelled hollow structures are promising electrode materials for rechargeable alkaline batteries due to their abundant redox centers and electrochemically active sites.
Wang, Dan   +11 more
core   +1 more source

Sulfide

open access: yes, 2022
In den Beiheften des Halleschen Jahrbuchs für Geowissenschaften werden Abschlussarbeiten, Forschungsergebnisse und Sammelschriften veröffentlicht.Die Beihefte erscheinen in unregelmäßiger Reihenfolge parallel zum Halleschen Jahrbuch für ...
openaire   +2 more sources

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

open access: yesAdvanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang   +12 more
wiley   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

open access: yesAdvanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li   +5 more
wiley   +1 more source

ToxGuide for hydrogen sulfide (H2S) CAS# 7783-06-4

open access: yes
Reference: Agency for Toxic Substances and Disease Registry (ATSDR). 2016. Toxicological Profile for Hydrogen Sulfide and Carbonyl Sulfide. Atlanta, GA: U.S.

core   +1 more source

Functional and structural characterization of Aquifex aeolicus sulfide:quinone oxidoreductase

open access: yes, 2010
This work presents the first complete structure of the membrane protein sulfide:quinone oxidoreductase (SQR), obtained by X-ray crystallography. Its description is complemented by the results of biochemical and functional experiments. SQRs are ubiquitous
Marcia, Marco, Marcia, M.
core  

Recent Advances in Laser‐Induced Graphene‐Based Gas Sensors: From Sensing Mechanisms to Biomedical Applications

open access: yesAdvanced Science, EarlyView.
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Md Abu Sayeed Biswas   +6 more
wiley   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

open access: yesAdvanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård   +19 more
wiley   +1 more source

New Chemical Strategies for prodrug preparations: from sulfide to doxorubicin

open access: yes, 2019
Prodrug is an often-used approach to facilitate the delivery of an active drug to an appropriate site with targeted release whenever possible. Proper prodrug design often relies on a few essential requirements: prodrug stability, triggered release, and ...
Zheng, Yueqin
core   +1 more source

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