Results 161 to 170 of about 77,925 (335)

Membran‐Bioreaktor‐Technik kombiniert mit nachgeschalteter Ozonung – Vergleich mit konventionellen Ozonanwendungen Combination of Membrane Bioreactor and Downstream Ozonation – A Comparison to Conventional Ozone Applications

Chemie Ingenieur Technik, EarlyView.
Kommunale Kläranlagen gelten als Haupteintragspfad organischer Mikroschadstoffe in die aquatische Umwelt. Ein Großteil der Arzneimittelrückstände und Industriechemikalien wird in Kläranlagen nicht oder nur teilweise entfernt. Um einen qualitativ höheren Kläranlagen‐Ablauf zu erzeugen, wird eine Kombination aus hybridem Teilstrom‐Membran‐Bioreaktor mit ...
Maximilian Werner, Jie Ji, Minyi Yin, Holger Lutze, Stefan Panglisch   +4 more
wiley   +1 more source

Effects of Sulfonamides and Azochloramid on Hemolytic Streptococci in Artificial Wounds of Rabbits [PDF]

, 1944
Thomas G. Lamberti, Roger S. Hubbard, E. Neter   +2 more
openalex   +1 more source

SULFONAMIDE-RESISTANT STAPHYLOCOCCI: CORRELATION OF IN VITRO SULFONAMIDE—RESISTANCE WITH SULFONAMIDE THERAPY 1 [PDF]

Journal of Clinical Investigation, 1944
Wesley W. Spink, Jean Jermsta Vivino
openaire   +3 more sources

Aminocholestane and Aminoandrostane Inhibitors of the SH2 Domain‐Containing Inositol 5’‐Phosphatase (SHIP)

ChemMedChem, Volume 20, Issue 8, April 14, 2025.
Analogs of the aminosteroid SHIP inhibitor 3α‐aminocholestane (3AC) have been synthesized and tested. Deletion of the C17 alkyl chain improves water solubility, however these analogs inhibit both SHIP1 and SHIP2. Enzyme kinetics imply that these aminosteroids are competitive inhibitors, and a model of the inhibitors within the active site of SHIP is ...
Angela M. Pacherille, Dennis R. Viernes, Chiara Pedicone, Sandra Fernandes, Otto M. Dungan, Shawn Dormann, Daniel R. Wallach, Raki Sudan, Robbie Brooks, Christopher M. Russo, Kyle T. Howard, Michael S. Cosgrove, William G. Kerr, John D. Chisholm   +13 more
wiley   +1 more source

THE RELATION BETWEEN SULFONAMIDE RESISTANCE AND p -AMINOBENZOIC ACID REQUIREMENT [PDF]

, 1953
H. Yaniv, Bernard D. Davis
openalex   +1 more source

Small‐Molecule KRAS Inhibitors by Tyrosine Covalent Bond Formation

ChemMedChem, Accepted Article.
The development of the KRAS G12C inhibitor sotorasib was a major advance towards drugging KRAS. However, the G12C mutation is only found in about 10% of tumors with a KRAS mutation. KRAS tyrosine amino acids could provide alternative sites for covalent drug development.
Alexander Landgraf, Robert Brenner, Mona Ghozayel, Khuchtumur Bum-Erdene, Giovanni Gonzalez-Gutierrez, Samy Meroueh   +5 more
wiley   +1 more source

APH Inhibitors that Reverse Aminoglycoside Resistance in Enterococcus casseliflavus

ChemMedChem, Volume 20, Issue 8, April 14, 2025.
Molecular dynamics simulations and in silico screening were used to identify non‐competitive inhibitors of APH, the enzymes that confer resistance to aminoglycoside antibiotics. A hit molecule showed activity against APH(2′′)‐IVa. Allosteric inhibition by the hit molecule and a two‐fold more potent analogue was confirmed by enzymatic measurements. Both
Elise Kaplan, Laurent Chaloin, Jean‐François Guichou, Kévin Berrou, Rahila Rahimova, Gilles Labesse, Corinne Lionne   +6 more
wiley   +1 more source

Growth Responses of a Sulfonamide-requiring Mutant Strain of Neurospora [PDF]

, 1947
Sterling Emerson
openalex   +1 more source

THE SULFONAMIDE-REQUIRING MUTANT OF NEUROSPORA: THREONINE-METHIONINE ANTAGONISM [PDF]

, 1950
Marko Zalokar
openalex   +1 more source

Synthesis of aromatic secondary diamines [PDF]

A series of N-methyl substituted aromatic polyamides derived from the secondary aromatic diamines, 4,4'-bis(methylamino)diphenylmethane, 3,3'-bis(methylamino) diphenylmethane, 4,4'-bis(methylamino)benzophenone or 3,3'-bis(methylamino)benzophenone and ...
Greenwood, T. D., Kahley, R. A., Wolfe, J. F.   +2 more
core   +1 more source