Results 231 to 240 of about 115,474 (373)

Synthesis of γ-alkylidene lactones <i>via</i> molecular stitching of carboxylic acids and olefins. [PDF]

Chem Sci
Crnovrsanin E, Mal S, van Gemmeren M.
europepmc   +1 more source

Novel Para‐Phenylenediamine‐Based Derivatives as Receptor Tyrosine Kinase‐like Orphan Receptor 1 (ROR1) Inhibitors: An In Vitro Preliminary Characterization

ChemMedChem, Volume 20, Issue 14, July 18, 2025.
ROR1 represents a promising target for the development of novel antiproliferative compounds, giving its high expression in different cancer cell lines. The present study describes the workflow leading to the design, synthesis, and characterization of a series of para‐phenylenediamine‐based compounds able to interact with the target kinase, inhibiting ...
Gerardina Smaldone, Maria Rosaria Miranda, Francesca Di Matteo, Valeria Napolitano, Michela Aliberti, Simona Musella, Veronica Di Sarno, Gianluigi Lauro, Giuseppe Bifulco, Giacomo Pepe, Giovanna Aquino, Mario Felice Tecce, Isabel Maria Gomez‐Monterrey, Pietro Campiglia, Carmine Ostacolo, Alessia Bertamino, Vincenzo Vestuto, Tania Ciaglia   +17 more
wiley   +1 more source

Effective synthesis of benzodiazepine sulfonamide-based MGAT2 inhibitors and evaluation of their antitumor activity. [PDF]

RSC Adv
Zhang Y, Li Y, Liu X, Wang Y, Zheng H, Zhou D.   +5 more
europepmc   +1 more source

Sustainable Approaches for the Protection and Deprotection of Functional Groups

Chemistry – A European Journal, Volume 31, Issue 40, July 17, 2025.
Shield: Protection and deprotection are key to selective synthesis, but conventional methods can lack sustainability. This review highlights electrochemical and photochemical strategies as greener alternatives, emphasizing their mechanisms, functional group tolerance, and broad synthetic utility.
Ju Ha Jin, Mina An, Minki Jeon, Jaejeong Kim, Sung Min Kang, Isaac Choi   +5 more
wiley   +1 more source

Streamlining SuFEx Inhibitor Development: A Unified Approach Using Photolabile and Orthogonal Sulfinate Protecting Groups

Angewandte Chemie, Volume 137, Issue 27, July 1, 2025.
This Study outlines the discovery and selection of sulfinate protecting groups (SPGs) based on their overall stability, ease of synthesis, and simple deprotection conditions, including two novel, photolabile SPGs that can be directly converted to the sulfonyl fluoride (SFs) using light and selectfluor.
Twinkle I. Patel, Makayla L. Williams, Yumeng Chi, Ramkrishna Laha, Matthew J. Moschitto   +4 more
wiley   +2 more sources

The In Vitro Effects of N-Substituted p -Aminobenzoic Acid Derivatives upon Sulfonamides [PDF]

, 1944
G. R. Goetchius, C. A. Lawrence
openalex   +1 more source

Intramolecular N-O Bond Formation for the Synthesis of <i>N</i>-Alkyl and <i>N</i>-Aryl Isoxazolidines. [PDF]

J Am Chem Soc
Solecki M, Crich D.
europepmc   +1 more source

Asymmetric Benzene Sulfonamide Sodium Salt Enabling Stable Cycling in Solid‐State Sodium Metal Batteries

ChemSusChem, Volume 18, Issue 14, July 17, 2025.
A novel sodium salt, sodium (benzenesulfonyl)(trifluoromethanesulfonyl) imide, is developed for all‐solid‐state sodium metal batteries. It offers a high sodium‐ion transference number and stability with sodium metal . Combined with poly(ethylene oxide), it forms strong solid polymer electrolytes that suppress dendrite growth and polarization.
Itziar Aldalur, Jorge Luis Olmedo‐Martinez, Lorena Garcia, Asier Fernández De Añastro, Koray Cavusoglu, David Mecerreyes, Alejandro Jesus Müller, Michel Armand, María Martinez‐Ibañez   +8 more
wiley   +1 more source

Performance-Enhancing Asymmetric Catalysis Driven by Achiral Counterion Design. [PDF]

J Am Chem Soc
Deng Z, Payne JL, Vishe M, Jan JEL, Funk CM, Johnston JN.   +5 more
europepmc   +1 more source

Palladium‐Catalyzed Dual Csp2─Csp3 Bond Formation: A Versatile Platform for the Synthesis of Benzo‐Fused Heterocycles

Advanced Science, Volume 12, Issue 25, July 3, 2025.
Pd(II)/Cu(I) co‐catalyzed dual Csp2─Csp3 bonds construction from unactivated alkenes and arylsulfonyl chlorides to access benzo‐fused heterocycles with high efficiency and chemoselectivity. Abstract Transition‐metal‐catalyzed transformations offer a powerful approach to rapidly synthesize complex benzo‐fused heterocycles, crucial for drug and material ...
Jiahui Huang, Yuantao You, Yijian Ma, Xingying He, Yixiao Li, Arunachalam Kesavan, Chengzhi Jin, Chengshuo Shen, Min Zhang, Kedong Yuan   +9 more
wiley   +1 more source