Results 271 to 280 of about 29,796 (299)

Bifidobacterium longum CCFM1206 Promotes the Biotransformation of Glucoraphanin to Sulforaphane That Contributes to Amelioration of Dextran-Sulfate-Sodium-Induced Colitis in Mice.

Journal of Agricultural and Food Chemistry, 2023
Glucoraphanin, rich in broccoli seed extract (BSE), is generally inert but can be biotransformed into active sulforaphane by gut bacteria. This study aimed to screen probiotics with glucoraphanin-metabolizing ability and explore the effect of a ...
Jiaying Wu, Shumao Cui, Xin Tang, Qiuxiang Zhang, Yan Jin, Jianxin Zhao, Bingyong Mao, Hao Zhang   +7 more
semanticscholar   +1 more source

Sulforaphane: A review of its therapeutic potentials, advances in its nanodelivery, recent patents, and clinical trials

Phytotherapy Research, 2021
Traditionally, herbal supplements have shown an exceptional potential of desirability for the prevention of diseases and their treatment. Sulforaphane (SFN), an organosulfur compound belongs to the isothiocyanate (ITC) group and is mainly found naturally
Bharti Mangla, S. Javed, M. Sultan, Pankaj Kumar, K. Kohli, A. Najmi, H. A. Alhazmi, M. Al Bratty, W. Ahsan   +8 more
semanticscholar   +1 more source

Antimetastatic activity of Sulforaphane

Life Sciences, 2006
The effect of Sulforaphane on the inhibition of lung metastasis induced by B16F-10 melanoma cells was studied in C57BL/6 mice by three different modalities of administration-simultaneous, prophylactic and after tumour developed. Of this simultaneous mode of Sulforaphane administration was found to be most effective.
P, Thejass, Girija, Kuttan
openaire   +2 more sources

Biochemical Characterization of a Novel Myrosinase Rmyr from Rahnella inusitata for High-Level Preparation of Sulforaphene and Sulforaphane.

Journal of Agricultural and Food Chemistry, 2022
Myrosinase is a biotechnological tool for the preparation of sulforaphane and sulforaphene with a variety of excellent biological activities. In this study, a gene encoding the novel glycoside hydrolase family 3 (GH3) myrosinase Rmyr from Rahnella ...
Lili Wang, Hong Jiang, Yanjun Qiu, Yueyang Dong, H. Hamouda, M. A. Balah, Xiangzhao Mao   +6 more
semanticscholar   +1 more source

Sulforaphane and prostate cancer interception

Drug Discovery Today, 2014
Whereas much attention is focused on distinguishing newly diagnosed prostate cancers that will progress to become aggressive forms of the disease from those that will remain indolent, it is also appropriate to explore therapeutic and lifestyle interventions to reduce the risk of progression.
Maria H, Traka, Antonietta, Melchini, Richard F, Mithen   +2 more
openaire   +2 more sources

Synergistic Effect of Combination of Phenethyl Isothiocyanate and Sulforaphane or Curcumin and Sulforaphane in the Inhibition of Inflammation

Pharmaceutical Research, 2008
Accumulating evidence from epidemiologic and clinical studies indicates that chronic inflammatory disorders harbor an increased risk of cancer development. Curcumin (CUR) has been strongly linked to the anti-inflammatory effect. On the other hand, isothiocyanates such as sulforaphane (SFN) and phenethyl isothiocyanate (PEITC) are strong phase-II ...
Ka Lung, Cheung, Tin Oo, Khor, Ah-Ng, Kong   +2 more
openaire   +2 more sources

Approaches for enhancing the stability and formation of sulforaphane

Food Chemistry, 2021
The isothiocyanate sulforaphane (SF) is one of the most potent naturally occurring Phase 2 enzymes inducers derived from brassica vegetables like broccoli, cabbage, brussel sprouts, etc. Ingestion of broccoli releases SF via hydrolysis of glucoraphanin (GRP) by plant myrosinase and/or intestinal microbiota.
Wu, Yuanfeng, Lv, Chengzhi, Zou, Ligen, Sun, Juan, Song, Xinjie, Zhang, Yao, Mao, Jianwei   +6 more
openaire   +2 more sources

A new validated HPLC method for the determination of sulforaphane: application to study pharmacokinetics of sulforaphane in rats

Biomedical Chromatography, 2015
AbstractA simple, accurate and reproducible high‐performance liquid chromatography (HPLC) method has been developed and validated for the quantification of sulforaphane (SF) in rat plasma. The method involves a simple liquid–liquid extraction procedure to extract both SF and 7‐hyrdoxycoumarin, the internal standard.
Chau, Ong, Fawzy, Elbarbry
openaire   +2 more sources

Thermal Degradation of Sulforaphane in Aqueous Solution

Journal of Agricultural and Food Chemistry, 1999
Sulforaphane, a cancer chemopreventive agent identified from broccoli, was degraded in an aqueous solution at 50 and 100 degrees C. The reaction mixtures were extracted with methylene chloride and analyzed by gas chromatography (GC) and gas chromatography/mass spectrometry (GC/MS).
Rosen, RT, Jin, Y, Wang, M, Ho, CT
openaire   +4 more sources

Evolution of sulforaphane content in sulforaphane-enriched broccoli during tray drying

Journal of Food Engineering, 2016
Abstract Sulforaphane is a natural anticancer compound found in broccoli that comes from hydrolysis of glucoraphanin. Conversion of glucoraphanin to sulforaphane has been optimized, however, its use as functional ingredient is limited because sulforaphane is thermo-labile.
Andrea Mahn, Constanza Martin, Alejandro Reyes, Aldo Saavedra   +3 more
openaire   +1 more source