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Antileukemic Activity of Sulforaphane
2016The biological complexity of cancer offers numerous targets for antineoplastic therapies. Diet is a common source of biologically active compounds. Many studies demonstrated an inverse relation between the consumption of vegetables and the risk of cancer.
CATANZARO, ELENA, FIMOGNARI, CARMELA
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Journal of Agricultural and Food Chemistry, 2001
Epidemiological and laboratory studies suggest that dietary broccoli may prevent or delay a variety of cancers. Broccoli and other crucifers contain a relatively unique family of secondary metabolites called glucosinolates. Glucoraphanin, the major glucosinolate in broccoli, is hydrolyzed by an endogenous plant myrosinase to form either the potent ...
N V, Matusheski, E H, Jeffery
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Epidemiological and laboratory studies suggest that dietary broccoli may prevent or delay a variety of cancers. Broccoli and other crucifers contain a relatively unique family of secondary metabolites called glucosinolates. Glucoraphanin, the major glucosinolate in broccoli, is hydrolyzed by an endogenous plant myrosinase to form either the potent ...
N V, Matusheski, E H, Jeffery
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Journal of Agricultural and Food Chemistry, 2001
An extraction and preparative HPLC method has been devised to simultaneously purify sulforaphane and sulforaphane nitrile from the seed of Brassica oleracea var. italica cv. Brigadier. The seed was defatted with hexane, dried, and hydrolyzed in deionized water (1:9) for 8 h. The hydrolyzed seed meal was salted and extracted with methylene chloride. The
N V, Matusheski +5 more
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An extraction and preparative HPLC method has been devised to simultaneously purify sulforaphane and sulforaphane nitrile from the seed of Brassica oleracea var. italica cv. Brigadier. The seed was defatted with hexane, dried, and hydrolyzed in deionized water (1:9) for 8 h. The hydrolyzed seed meal was salted and extracted with methylene chloride. The
N V, Matusheski +5 more
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Dual Roles of Sulforaphane in Cancer Treatment
Anti-Cancer Agents in Medicinal Chemistry, 2012Sulforaphane (SFN), one of naturally occurring isothiocyanates (ITCs), has huge cancer chemopreventive potential. It modulates cell death, cell cycle, angiogenesis, susceptibility to carcinogens, invasion and metastasis and possesses antioxidant activities.
Tongzhen, Xu +3 more
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Journal of Agricultural and Food Chemistry, 1998
Phytochemicals, especially the secondary metabolites synthesized by plants, play key roles in human nutrition, health, wellness, and disease prevention.
William C. K. Chiang +2 more
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Phytochemicals, especially the secondary metabolites synthesized by plants, play key roles in human nutrition, health, wellness, and disease prevention.
William C. K. Chiang +2 more
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Effects of sulforaphane in the central nervous system
European Journal of Pharmacology, 2019Sulforaphane (SFN) is an active component extracted from vegetables like cauliflower and broccoli. Activation of the nuclear factor (erythroid-derived 2)-like 2 (Nrf2) signaling is a common mechanism for the anti-oxidative and anti-inflammatory activity of some herb-derived compounds, such as icariin and berberine.
Chao Huang +5 more
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Potential effects of sulforaphane to fight obesity
Journal of the Science of Food and Agriculture, 2018AbstractObesity is linked to the onset of many diseases such as diabetes mellitus, cardiovascular diseases and cancer, among others. The prevalence of obesity nearly doubled worldwide between 1980 and 2014. Simultaneously, in the last decade, the effects of sulforaphane as a potential treatment for obesity have been investigated, with promising results.
Tânia Martins +6 more
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