Results 41 to 50 of about 163,760 (356)
Journal of Computational Engineering, 2015 A new estimate of the probability density function (PDF) of the sum of a random number of independent and identically distributed (IID) random variables is shown. The sum PDF is represented as a sum of normal PDFs weighted according to the PDF.
A. Gifuni +3 more
semanticscholar +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
On the Distribution of the Sum of Independent Random Variables and Its Application
International Journal of Information and Communication Technology Research, 2009 An approximate analytical method for the evaluation of the cumulative distribution function (CDF) of the sum of L independent random variables (RVs) is presented.
Hossein Samimi, Paeiz Azmi
doaj
The discount version of large deviations for a randomly indexed sum of random variables
Lietuvos Matematikos Rinkinys, 2011 In this paper, we consider a compound random variable Z = \sum^N_{j=1} vjXj , where 0 < v < 1, Z = 0, if N = 0. It is assumed that independent identically distributed random variables X1,X2, . . .
Aurelija Kasparavičiūtė +1 more
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Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Folia Oeconomica Stetinensia, 2015 In the article the author considers and analyzes operations and functions on risk variables. She takes into account the following variables: the sum of risk variables, its product, multiplication by a constant, division, maximum, minimum and median of a ...
Khemissi Eliza Anna
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Approximations to the distribution of sum of independent non-identically gamma random variables
, 2015 Calculating the sum of independent non-identically distributed random variables is necessary in the scientific field. Computing the probability of the corresponding significance point is important in cases that have a finite sum of random variables ...
H. Murakami
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source