Results 121 to 130 of about 898,395 (346)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Intensity enhancement of O VI ultraviolet emission lines in solar spectra due to opacity

, 2014
Opacity is a property of many plasmas, and it is normally expected that if an emission line in a plasma becomes optically thick, its intensity ratio to that of another transition that remains optically thin should decrease.
Bowler, L. A., Britton, J., Doyle, J. G., Keenan, F. P., Madjarska, M. S., Mathioudakis, M., McCrink, L., Rose, S. J.   +7 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Numerical modeling of wave-induced liquefaction around a gravity-based structure

Frontiers in Built Environment
Residual liquefaction, a significant issue in marine engineering, results from accumulated pore-water pressure in the seabed due to cyclic shear stresses, which compromises soil stability.
V. S. Ozgur Kirca, V. S. Ozgur Kirca, Mert Angin, B. Mutlu Sumer   +3 more
doaj   +1 more source

The Spectroscopic Footprint of the Fast Solar Wind

, 2010
We analyze a large, complex equatorial coronal hole (ECH) and its immediate surroundings with a focus on the roots of the fast solar wind. We start by demonstrating that our ECH is indeed a source of the fast solar wind at 1AU by examining in situ plasma
Bart De Pontieu, Beckers, Chae, Cranmer, Cranmer, Dammasch, Davey, De Pontieu, De Pontieu, De Pontieu, Fleck, Habbal, Hansteen, Leamon, Leamon, McIntosh, McIntosh, McIntosh, McIntosh, McIntosh, McIntosh, McIntosh, Patsourakos, Robert J. Leamon, Rouppe van der Voort, Schrijver, Scott W. McIntosh, Suzuki, Suzuki, Tian, Tu, Verdini, Verdini, Wilhelm, Xia, Zacharias   +35 more
core   +1 more source

Predicting and Comparing the Subjective Health Experience of Older Cancer Survivors and Non‐Cancer Survivors: A Modeling Approach

Aging and Cancer, EarlyView.
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst, Sjaak Bloem, Eline J. Mertens, Nathascha Hanzen, Michel van Agthoven   +4 more
wiley   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Does the Exchange Rate Really Affect Consumer Spending? [PDF]

This paper examines the extent to which changes in imports or exports of U.S. consumer goods and services occurs in response to a change in the exchange rate, 1960 -2000. The data used are taken from the Economic Report of the President, 2002.
John J. Heim
core  

Radiance and Doppler shift distributions across the network of the quiet Sun

, 2008
The radiance and Doppler-shift distributions across the solar network provide observational constraints of two-dimensional modeling of transition-region emission and flows in coronal funnels.
He, J. -S., Tian, H., Tu, C. -Y., Xia, L. -D.   +3 more
core   +1 more source

Accelerated Progression of Gait Impairment in Parkinson's Disease and REM Sleep Without Atonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with Parkinson's disease (PD) and rapid eye movement (REM) sleep without atonia (RSWA) often have more severe gait disturbances compared to PD without RSWA. The association between the presence and expression of RSWA and the rate of progression of gait impairment in PD is unknown.
Sommer L. Amundsen‐Huffmaster, Jae Woo Chung, Maria E. Linn‐Evans, Matthew N. Petrucci, Chiahao Lu, Destiny J. Weaver, Joshua De Kam, Scott E. Cooper, Paul J. Tuite, Aleksandar Videnovic, Michael J. Howell, Colum D. MacKinnon   +11 more
wiley   +1 more source