Results 91 to 100 of about 3,292,350 (321)
Optimization Monte Carlo: Efficient and Embarrassingly Parallel Likelihood-Free Inference [PDF]
, 2015 We describe an embarrassingly parallel, anytime Monte Carlo method for likelihood-free models. The algorithm starts with the view that the stochasticity of the pseudo-samples generated by the simulator can be controlled externally by a vector of random ...
Meeds, Edward, Welling, Max
core +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Sea stack plots: Replacing bar charts with histograms
Ecology and EvolutionGraphs in research articles can increase the comprehension of statistical data but may mislead readers if poorly designed. We propose a new plot type, the sea stack plot, which combines vertical histograms and summary statistics to represent large ...
Alice Dorothy Stuart +3 more
doaj +1 more source
Fully Bayesian tests of neutrality using genealogical summary statistics
BMC Genetics, 2008 Background Many data summary statistics have been developed to detect departures from neutral expectations of evolutionary models. However questions about the neutrality of the evolution of genetic loci within natural populations remain difficult to ...
Drummond Alexei J, Suchard Marc A
doaj +1 more source
Partially Exchangeable Networks and Architectures for Learning Summary Statistics in Approximate Bayesian Computation [PDF]
, 2019 We present a novel family of deep neural architectures, named partially exchangeable networks (PENs) that leverage probabilistic symmetries. By design, PENs are invariant to block-switch transformations, which characterize the partial exchangeability ...
Frellsen, Jes +3 more
core +2 more sources
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
European comparative data on Europe 2020 & People with Disabilities [PDF]
, 2013 Summary and Conclusions Europe 2020 is a new strategy for the EU which aims among others to deliver high levels of employment and strengthen social cohesion. Monitoring achievements through statistics is integral part of the Europe 2020 strategy.
Academic Network of European Disability Experts (ANED) +2 more
core +1 more source
Erich Leo Lehmann---A glimpse into his life and work
, 2011 Through the use of a system-building approach, an approach that includes finding common ground for the various philosophical paradigms within statistics, Erich L.
Rojo, Javier
core +1 more source