Results 161 to 170 of about 3,292,350 (321)
Full summary statistics of mixQTL for GTEx v8 Colon_Transverse
Yanyu Liang +4 more
openalex +2 more sources
Powerful Statistical Inference for Nested Data Using Sufficient Summary Statistics [PDF]
Irene Dowding, Stefan Haufe
openalex +1 more source
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
TidyGWAS: a scalable approach for standardized cleaning of genome-wide association study summary statistics. [PDF]
Harder A +4 more
europepmc +1 more source
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Network construction using sparse Gaussian graphical model based on GWAS summary statistics. [PDF]
Subedi M, Cao X, Kim BJ, Sha Q.
europepmc +1 more source
Crystallographic parameters, data collection statistics and refinement summary.
Vulliez-Le Normand Brigitte +10 more
openalex +2 more sources

