Results 171 to 180 of about 3,753,733 (329)

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

LiMA: Robust inference of molecular mediation from summary statistics. [PDF]

Am J Hum Genet
Lepik K, Auwerx C, Sadler MC, van der Graaf A, Ojavee SE, Kutalik Z.   +5 more
europepmc   +1 more source

Detailed information on the univariate genome-wide association study (GWAS) summary statistics included in the study.

Pan Shen (5957090), Hao Xiong (86981), Qing-Hua Luo (22446487), Yi-Fan Ding (1453186), Wei Ge (39218), Wu Liao (18843741), Lei-Chang Zhang (22446490)   +6 more
openalex   +1 more source

A Bayesian hierarchical variable selection prior for pathway‐based GWAS using summary statistics

, 2019
Yi Yang, Saonli Basu, Lin Zhang
openalex   +2 more sources

Improved Use of Small Reference Panels for Conditional and Joint Analysis with GWAS Summary Statistics [PDF]

, 2018
Yangqing Deng, Wei Pan
openalex   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

A scalable framework for identifying allelic series from summary statistics. [PDF]

Am J Hum Genet
McCaw ZR, Gao J, Dey R, Tucker S, Zhang Y, insitro Research Team, Gronsbell J, Li X, Fox E, O'Dushlaine C, Soare TW.   +10 more
europepmc   +1 more source

Model Summary for good fit of the data Statistics and Coefficients for Risks associated with supply chain performance in pharmaceutical company of Addis Ababa, Ethiopia, 2023 (N=172).

Dinku Mechal (21273002), Bekele Boche (12235967)   +1 more
openalex   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Mendelian Randomization Studies of Myopia: Choosing the Right Summary Statistics. [PDF]

Invest Ophthalmol Vis Sci
Nguyen TN, Terry L, Guggenheim JA.
europepmc   +1 more source