Results 181 to 190 of about 3,753,733 (329)

The summary statistics (mean ± S.E) of MSE of regression coefficients regarding proposed and other studied estimators for p = 15 and ρ = 0.9.

Aiman Tahir (21485064), Maryam Ilyas (9411385)   +1 more
openalex   +1 more source

Appendix A. Summary statistics for the distribution of trait values for both global data sets and Jasper Ridge (54 woody species).

, 2016
William K. Cornwell, Dylan W. Schwilk, David D. Ackerly   +2 more
openalex   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

GENEasso: a curated resource of credible disease-gene associations across complex diseases from GWAS summary statistics. [PDF]

Nucleic Acids Res
Jiang T, Shao M, Wang J, Wu P, Zhu C, Tang R, Cao C, Gu N.   +7 more
europepmc   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

TidyGWAS: a scalable approach for standardized cleaning of genome-wide association study summary statistics. [PDF]

Bioinform Adv
Harder A, Guintivano J, Pasman JA, Sullivan PF, Lu Y.   +4 more
europepmc   +1 more source

Prospects of Fine-Mapping Trait-Associated Genomic Regions by Using Summary Statistics from Genome-wide Association Studies [PDF]

, 2017
Christian Benner, Aki S. Havulinna, Marjo‐Riitta Järvelin, Veikko Salomaa, Samuli Ripatti, Matti Pirinen   +5 more
openalex   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Network construction using sparse Gaussian graphical model based on GWAS summary statistics. [PDF]

Sci Rep
Subedi M, Cao X, Kim BJ, Sha Q.
europepmc   +1 more source