Results 11 to 20 of about 3,292,350 (321)
Overestimated prediction using polygenic prediction derived from summary statistics [PDF]
BMC Genomic Data, 2023 Background When polygenic risk score (PRS) is derived from summary statistics, independence between discovery and test sets cannot be monitored. We compared two types of PRS studies derived from raw genetic data (denoted as rPRS) and the summary ...
David Keetae Park +8 more
doaj +2 more sources
Summary statistics for inhomogeneous marked point processes [PDF]
, 2014 We propose new summary statistics for intensity-reweighted moment stationary marked point processes with particular emphasis on discrete marks. The new statistics are based on the n-point correlation functions and reduce to cross J- and D-functions when ...
Cronie, O., van Lieshout, M. N. M.
core +2 more sources
The variant call format provides efficient and robust storage of GWAS summary statistics
Genome Biology, 2021 GWAS summary statistics are fundamental for a variety of research applications yet no common storage format has been widely adopted. Existing tabular formats ambiguously or incompletely store information about genetic variants and associations, lack ...
Matthew S. Lyon +5 more
doaj +1 more source
SumStatsRehab: an efficient algorithm for GWAS summary statistics assessment and restoration
BMC Bioinformatics, 2022 Background Generating polygenic risk scores for diseases and complex traits requires high quality GWAS summary statistic files. Often, these files can be difficult to acquire either as a result of unshared or incomplete data.
Mykyta Matushyn +11 more
doaj +1 more source
Sharing GWAS summary statistics results in more citations
Communications Biology, 2023 A review of citation rates from genomic studies in the GWAS Catalog suggests that sharing summary statistics results, on average, in ~81.8% more citations, highlighting a benefit of publicly sharing GWAS summary statistics.
Guillermo Reales, Chris Wallace
doaj +1 more source
An Omnibus Test for Detecting Multiple Phenotype Associations Based on GWAS Summary Level Data
Frontiers in Genetics, 2021 Abundant Genome-wide association study (GWAS) findings have reflected the sharing of genetic variants among multiple phenotypes. Exploring the association between genetic variants and multiple traits can provide novel insights into the biological ...
Wei Liu, Yunshan Guo, Zhonghua Liu
doaj +1 more source
Human microbiome privacy risks associated with summary statistics.
PLoS ONE, 2021 Recognizing that microbial community composition within the human microbiome is associated with the physiological state of the host has sparked a large number of human microbiome association studies (HMAS).
Jae-Chang Cho
doaj +1 more source
Dealing with missing standard deviation and mean values in meta-analysis of continuous outcomes: a systematic review [PDF]
, 2018 Background: Rigorous, informative meta-analyses rely on availability of appropriate summary statistics or individual participant data. For continuous outcomes, especially those with naturally skewed distributions, summary information on the mean or ...
A Patil +32 more
core +3 more sources
Summary statistics for fossil spider species taxonomy
ZooKeys, 2012 Spiders (Araneae) are one of the most species-rich orders on Earth today, and also have one of the longest geological records of any terrestrial animal groups, as demonstrated by their extensive fossil record.
David Penney, Jason Dunlop, Yuri Marusik
doaj +1 more source