Results 21 to 30 of about 3,292,350 (321)

Assessment of the causal association between celiac disease and cardiovascular diseases

Frontiers in Cardiovascular Medicine, 2022
BackgroundEpidemiological studies have reported inconsistent results of the association between celiac disease (CD) and cardiovascular diseases. Moreover, the causality remains largely unknown.
Jian Huang
doaj   +1 more source

Computationally efficient meta-analysis of gene-based tests using summary statistics in large-scale genetic studies. [PDF]

Nat Genet
Joseph TA, Mbatchou J, Ghosh A, Marcketta A, Gillies CE, Tang J, Nakka P, Zhang X, Kosmicki JA, Sidore C, Gurski L, Regeneron Genetics Center, Ghoussaini M, Ferreira MAR, Abecasis G, Marchini J.   +15 more
europepmc   +3 more sources

Inferring HIV Transmission Network Determinants Using Agent-Based Models Calibrated to Multi-Data Sources

Mathematics, 2021
(1) Background: Calibration of Simpact Cyan can help to improve estimates related to the transmission dynamics of the Human Immunodeficiency Virus (HIV).
David Niyukuri, Trust Chibawara, Peter Suwirakwenda Nyasulu, Wim Delva   +3 more
doaj   +1 more source

Intrinsic dimension as a multi-scale summary statistics in network modeling. [PDF]

Sci Rep
Macocco I, Mira A, Laio A.
europepmc   +3 more sources

On Exact and Approximate Approaches for Stochastic Receptor-Ligand Competition Dynamics—An Ecological Perspective

Mathematics, 2020
Cellular receptors on the cell membrane can bind ligand molecules in the extra-cellular medium to form ligand-bound monomers. These interactions ultimately determine the fate of a cell through the resulting intra-cellular signalling cascades.
Polly-Anne Jeffrey, Martín López-García, Mario Castro, Grant Lythe, Carmen Molina-París   +4 more
doaj   +1 more source

A genome-wide cross-cancer meta-analysis highlights the shared genetic links of five solid cancers

Frontiers in Microbiology, 2023
Breast, ovarian, prostate, lung, and head/neck cancers are five solid cancers with complex interrelationships. However, the shared genetic factors of the five cancers were often revealed either by the combination of individual genome-wide association ...
Hongping Guo, Wenhao Cao, Yiran Zhu, Tong Li, Boheng Hu   +4 more
doaj   +1 more source

A Comparative Review of Dimension Reduction Methods in Approximate Bayesian Computation [PDF]

, 2013
Approximate Bayesian computation (ABC) methods make use of comparisons between simulated and observed summary statistics to overcome the problem of computationally intractable likelihood functions.
Blum, M. G. B., Nunes, M. A., Prangle, D., Sisson, S. A.   +3 more
core   +4 more sources

A multivariate approach to assess the genetic diversity in finger millet [Eleusine coracana (L.) Gaertn.] germplasm accessions

Electronic Journal of Plant Breeding, 2023
Finger millet [Eleusine coracana (L.) Gaertn.], a staple cereal amongst the rural population of large parts of Africa and South Asia. It is well-known for its nutritional status, especially abundant quantities of iron and calcium.
T. E. Nagaraja1*, Sujata Bhat2, C. Nandini3, H. S. Saritha4 and S. Gazala Parveen5
doaj   +1 more source

Measuring the degree of starshape in genealogies - summary statistics and demographic inference [PDF]

, 2009
The degree of starshape of a genealogy is readily detectable using summary statistics and can be taken as a surrogate for the effect of past demography and other non-neutral forces.
Baudry, Braverman, Di Rienzo, Fay, Fu, Fu, Galtier, Glinka, Harpending, Hudson, Jennings, JEROME KELLEHER, Kliman, KONRAD LOHSE, Kuhner, Pluzhnikov, Schierup, Schneider, Simonsen, Slatkin, Tajima, Tajima, Uyenoyama   +22 more
core   +1 more source

Using Summary Statistics to Model Multiplicative Combinations of Initially Analyzed Phenotypes With a Flexible Choice of Covariates

Frontiers in Genetics, 2021
While the promise of electronic medical record and biobank data is large, major questions remain about patient privacy, computational hurdles, and data access.
Jack M. Wolf , Jason Westra, Nathan Tintle, Nathan Tintle   +3 more
doaj   +1 more source