Results 51 to 60 of about 3,753,733 (329)

Ecological Insights from Spatial Pattern Analysis: Halocnemum strobilaceum and Climacoptera turcomanica in Golestan's Saline and Alkaline Rangelands [PDF]

Desert
Halophytes and other salt-tolerant plants in rangeland ecosystems play an important role in environmental protection and food security. The spatial point pattern analyses of these plants in arid and semi-arid areas provide valuable information about how ...
Mojgansadat Azimi, Omolbanin Ebrahimi, Narges Kariminejad, Vahideh Riyazinia, Mohadeseh Amiri, Giandiego Campetella   +5 more
doaj   +1 more source

From GWAS to Gene: Transcriptome-Wide Association Studies and Other Methods to Functionally Understand GWAS Discoveries

Frontiers in Genetics, 2021
Since their inception, genome-wide association studies (GWAS) have identified more than a hundred thousand single nucleotide polymorphism (SNP) loci that are associated with various complex human diseases or traits.
Binglan Li, Marylyn D. Ritchie, Marylyn D. Ritchie   +2 more
doaj   +1 more source

Simultaneous estimation of bi-directional causal effects and heritable confounding from GWAS summary statistics

Nature Communications, 2020
Mendelian Randomisation (MR) is an increasingly popular approach that estimates the causal effect of risk factors on complex human traits. While it has seen several extensions that relax its basic assumptions, most suffer from two major limitations ...
Liza Darrous, N. Mounier, Z. Kutalik
semanticscholar   +1 more source

Construction and Clinical Translation of Causal Pan-Cancer Gene Score Across Cancer Types

Frontiers in Genetics, 2021
Pan-cancer strategy, an integrative analysis of different cancer types, can be used to explain oncogenesis and identify biomarkers using a larger statistical power and robustness.
Shiyue Tao, Xiangyu Ye, Lulu Pan, Minghan Fu, Peng Huang, Zhihang Peng, Sheng Yang   +6 more
doaj   +1 more source

Spatial pattern analysis of Montpellier maple (Acer monspessulanum L.) on steep slopes in Zagros (Case study: Firoozabad, Fars province) [PDF]

تحقیقات جنگل و صنوبر ایران, 2017
Topography is recognized as one of the effective drivers in spatial pattern of trees scattered on steep slopes. Topography influences spatial distribution of trees by changes in light availability, soil moisture and microclimate.
Azita Alipour, Seyyed Yousef Erfanifard
doaj   +1 more source

Summary statistics in auditory perception [PDF]

Nature Neuroscience, 2013
Sensory signals are transduced at high resolution, but their structure must be stored in a more compact format. Here we provide evidence that the auditory system summarizes the temporal details of sounds using time-averaged statistics. We measured discrimination of 'sound textures' that were characterized by particular statistical properties, as ...
Schemitsch, Michael, Simoncelli, Eero P, McDermott, Josh   +2 more
openaire   +4 more sources

A Quality Improvement Initiative to Standardize Pneumocystis jirovecii Pneumonia Prophylaxis in Pediatric Patients With Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar, Denise M. Connolly, Ellen Kellington, Elyse Zelunka, Karla Kerrigan, Furqan Shaikh, Paul C. Nathan, Meredith S. Irwin, Sarah Cohen‐Gogo   +8 more
wiley   +1 more source

Optimal Summary Statistics for X-ray Polarization

The Open Journal of Astrophysics
We develop two new highly efficient estimators to measure the polarization (Stokes parameters) in experiments that constrain the position angle of individual photons such as scattering and gas-pixel-detector polarimeters, and analyse in detail a ...
Jeremy Heyl, Denis González-Caniulef, Ilaria Caiazzo   +2 more
doaj   +1 more source

Matrix Metalloproteinases in Relation to Bone Mineral Density: A Two-Sample Mendelian Randomization Study

Frontiers in Genetics, 2021
Background: We aimed at investigating causal associations between matrix metalloproteinases (MMPs) and bone mineral density (BMD) by the Mendelian randomization (MR) analysis.Methods: From genome-wide association studies of European ancestry, we selected
Xin Lv, Pengfei Wu, Pengfei Wu, Shipeng Xiao, Wan Zhang, Yawei Li, Bolin Ren, Bolin Ren, Zhihong Li, Zhihong Li, Kun Xia, Kun Xia, Kun Xia, Bing Wang   +13 more
doaj   +1 more source

Integrative differential expression and gene set enrichment analysis using summary statistics for scRNA-seq studies

Nature Communications, 2020
Differential expression (DE) analysis and gene set enrichment (GSE) analysis are commonly applied in single cell RNA sequencing (scRNA-seq) studies. Here, we develop an integrative and scalable computational method, iDEA, to perform joint DE and GSE ...
Ying Ma, Shiquan Sun, Xuequn Shang, Evan T. Keller, Mengjie Chen, Xiaoping Zhou   +5 more
semanticscholar   +1 more source