Results 51 to 60 of about 3,292,350 (321)

Functional summary statistics for point processes on the sphere with an application to determinantal point processes

open access: yes, 2016
We study point processes on $\mathbb S^d$, the $d$-dimensional unit sphere $\mathbb S^d$, considering both the isotropic and the anisotropic case, and focusing mostly on the spherical case $d=2$.
Møller, Jesper, Rubak, Ege
core   +1 more source

Exploring the Genetic Correlation Between Growth and Immunity Based on Summary Statistics of Genome-Wide Association Studies

open access: yesFrontiers in Genetics, 2018
The relationship between growth and immune phenotypes has been presented in the context of physiology and energy allocation theory, but has rarely been explained genetically in humans.
Zhe Zhang   +15 more
doaj   +1 more source

Dried fruit intake causally protects against low back pain: A Mendelian randomization study

open access: yesFrontiers in Nutrition, 2023
BackgroundLow back pain is the leading cause of years lived with disability worldwide. The aim of this study was to evaluate whether dried fruit intake causally protects against low back pain using two-sample Mendelian randomization (MR).MethodsWe ...
Jian Huang, Zheng-Fu Xie
doaj   +1 more source

Clinical Correlates of Anxiety and Depression After Diagnosis of a Pediatric Brain Tumor

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background The prevalence and clinical correlates of symptoms of anxiety and depression in pediatric patients with brain tumors are not well described. We aimed to identify clinical characteristics that are correlated with elevated symptoms of anxiety and depression following initial diagnosis.
Bryony J. Lucas   +16 more
wiley   +1 more source

sumrep: A Summary Statistic Framework for Immune Receptor Repertoire Comparison and Model Validation

open access: yesFrontiers in Immunology, 2019
The adaptive immune system generates an incredible diversity of antigen receptors for B and T cells to keep dangerous pathogens at bay. The DNA sequences coding for these receptors arise by a complex recombination process followed by a series of ...
Branden J. Olson   +13 more
doaj   +1 more source

From GWAS to Gene: Transcriptome-Wide Association Studies and Other Methods to Functionally Understand GWAS Discoveries

open access: yesFrontiers in Genetics, 2021
Since their inception, genome-wide association studies (GWAS) have identified more than a hundred thousand single nucleotide polymorphism (SNP) loci that are associated with various complex human diseases or traits.
Binglan Li   +2 more
doaj   +1 more source

Lifestyle Behaviors and Cardiotoxic Treatment Risks in Adult Childhood Cancer Survivors

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Higher doses of anthracyclines and heart‐relevant radiotherapy increase cardiovascular disease (CVD) risk. This study assessed CVD and CVD risk factors among adult childhood cancer survivors (CCSs) across cardiotoxic treatment risk groups and examined associations between lifestyle behaviors and treatment risks.
Ruijie Li   +6 more
wiley   +1 more source

Causal effects of socioeconomic traits on frailty: a Mendelian randomization study

open access: yesFrontiers in Medicine
BackgroundThe relationship between socioeconomic status and frailty has been extensively investigated in the literature, but it remains unclear whether a causal relationship exists.
Jian Huang   +4 more
doaj   +1 more source

Can Theory Improve the Scope of Quantitative Metazoan Metabarcoding?

open access: yesDiversity, 2015
Using high-throughput sequencing approaches to quantify biodiversity has a number of hurdles, in particular that the number of reads for a given taxon may not be proportional to the number of individuals of that taxon in a sample.
John P. Wares, Paula Pappalardo
doaj   +1 more source

In silico mapping of coronary artery disease genes

open access: yesВавиловский журнал генетики и селекции, 2020
To date, more than 100 loci associated with coronary artery disease (CAD) have been detected in large-scale genome-wide studies. For some of the several hundreds of genes located in these loci, roles in the pathogenesis of the disease have been shown ...
I. V. Zorkoltseva   +4 more
doaj   +1 more source

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