Results 71 to 80 of about 3,292,350 (321)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou +10 more
wiley +1 more source
Alaska Energy Statistics 1960-2011 Final Report [PDF]
, 2013 This twenty-sixth edition of the Alaska Energy Statistics reconciles energy data from public sources and makes that data more easily available to the public and stakeholders.
Fay, Ginny +2 more
core
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
The Relationship Between Population Attributable Fraction and Heritability in Genetic Studies
Frontiers in Genetics, 2018 Population attributable fraction (PAF) has been widely used to quantify the proportion of disease risk in a population that can be attributed to risk factors in epidemiological studies.
Tao Wang +3 more
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Ensemble Coding of Crowd with Cross-Category Facial Expressions
Behavioral SciencesEnsemble coding allows observers to form an average to represent a set of elements. However, it is unclear whether observers can extract an average from a cross-category set.
Zhi Yang +5 more
doaj +1 more source
Applied Sciences, 2018 This paper presents a novel approach for acoustic scene classification based on efficient acoustic feature extraction using spectro-temporal descriptors fusion.
Jiaxing Ye +4 more
doaj +1 more source
Annual Compendium of Disability Statistics: 2015 [PDF]
, 2016 Statistics are a powerful tool—in research, policymaking, program evaluation, and advocacy. They are used to frame the issues, monitor current circumstances and progress, judge the effectiveness of policies and programs, make projections about the future,
Brucker, Debra L. +2 more
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source