Results 111 to 120 of about 9,230 (211)

Exercise‐induced miR‐126 expression improves vascular health in prediabetes: A randomized controlled trial

open access: yesExperimental Physiology, EarlyView.
Abstract In this study, we investigated whether a structured aerobic exercise programme could enhance microRNA‐126 (miR‐126) expression and improve subclinical atherosclerosis markers [carotid intima–media thickness (CIMT) and ankle–brachial index (ABI)] in individuals with prediabetes.
Elif Yildirim Ayaz   +9 more
wiley   +1 more source

Early adversity and the comorbidity between metabolic disease and psychopathology

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas   +1 more
wiley   +1 more source

ESM‐1 and GBP‐1 are associated with endothelial dysfunction: emerging biomarkers or key players in the pathophysiology of preeclampsia?

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Endothelial specific molecule‐1 (ESM‐1) and guanylate binding protein‐1 (GBP‐1) are proteins that are produced by activated/dysfunctional endothelial cells and are increased and decreased, respectively, during preeclampsia. It remains to be established whether ESM‐1 and GBP‐1 could potentially be included as biomarkers for the ...
Ines Pronk   +3 more
wiley   +1 more source

Ginsenoside Rg1 as a Multifunctional Therapeutic Agent: Pharmacological Properties, Molecular Mechanisms and Clinical Perspectives in Complementary Medicine. [PDF]

open access: yesFood Sci Nutr
Cortés H   +13 more
europepmc   +1 more source

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand   +2 more
wiley   +1 more source

TMEM16A channel signalling microdomains in the regulation of vascular function

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of TMEM16A channel signalling microdomains. Calcium influx or calcium release from the endoplasmic/sarcoplasmic reticulum (ER/SR) activates TMEM16A channels through interactions with regulatory proteins in vascular smooth muscle cells or endothelial cells. TMEM16A channel activation drives chloride efflux,
Fênix Araujo, Swapnil K. Sonkusare
wiley   +1 more source

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