Results 31 to 40 of about 4,161 (134)
Journal of the European Academy of Dermatology and Venereology, EarlyView.A matching‐adjusted indirect treatment comparison (MAIC) was conducted, comparing approved biologics for long‐term (48–52 weeks) treatment of moderate‐to‐severe hidradenitis suppurativa (HS). Using weighted patient‐level trial data allowed re‐estimation of relative bimekizumab efficacy compared with aggregate secukinumab and adalimumab trial data ...
Thrasyvoulos Tzellos +9 more
wiley +1 more source
Journal of the European Academy of Dermatology and Venereology, EarlyView.In adults with moderate AD post‐TCS and ‐TCI, who may otherwise be eligible for systemic therapy, 1.5% ruxolitinib cream improved clinical signs and symptoms in the TRuE‐AD4 study. Abstract Background In patients with moderate atopic dermatitis (AD), topical corticosteroids (TCS) and topical calcineurin inhibitors (TCI) often do not sufficiently ...
José Manuel Carrascosa +14 more
wiley +1 more source
Measuring success in HS treatment from the physician's and the patient's perspective
Journal of the European Academy of Dermatology and Venereology, EarlyView.Integrated clinician (HiSCR, IHS4, IHS4‐55, HS‐IGA) and patient (HiSQOL, DLQI) scores, combined with imaging‐based fibrosis and inflammation assessment, redefine treatment success in hidradenitis suppurativa by aligning treat‐to‐target strategies with both inflammatory control and irreversible structural damage.
Georgios Nikolakis +4 more
wiley +1 more source
ntRoot: Genetic Ancestry Inference Across Diverse Genomic Data Types
Current Protocols, Volume 6, Issue 11, November 2026.Abstract Genetic ancestry is encoded in our genomes, reflecting the genealogical history of individuals and populations. This information is increasingly recognized as an important variable in large‐scale population studies, where it is used to correct for population stratification, as well as in clinical applications, since disease risk can vary ...
Lauren Coombe +3 more
wiley +1 more source
Liquid Biopsy: Past, Present, and Future
MedComm, Volume 7, Issue 11, November 2026.Liquid biopsy has expanded from cancer genotyping to a broader strategy for probing both oncologic and nononcologic conditions through circulating analytes and multilayer molecular readouts. This review traces the field's past, present, and future—summarizing where liquid biopsy is most actionable today, why performance varies across contexts, and ...
Jiachen Liu +8 more
wiley +1 more source
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 11, November 2026.ABSTRACT Introduction Non‐infectious uveitis (NIU) is a chronic immune‐mediated ocular inflammatory disease that may cause irreversible visual impairment. The comparative efficacy and safety of systemic immunomodulatory therapies, including conventional agents and biologics, remain incompletely defined.
Kai‐Yang Chen +2 more
wiley +1 more source
High‐Dimensional Cumulative Sum Control Charts for Industrial Measurement Systems
Quality and Reliability Engineering International, Volume 42, Issue 7, Page 4342-4361, November 2026.ABSTRACT High dimensional sensing in modern factories and energy assets produces thousands of correlated signals. Detecting small process shifts is challenging because many classical multivariate charts lose power or become unstable. We present two cumulative sum procedures for two sample monitoring that remain effective when the number of variables is
Osama Alhadi +3 more
wiley +1 more source
Multiple Sclerosis and Viruses: « Liaisons Dangereuses »
Reviews in Medical Virology, Volume 36, Issue 6, November 2026.ABSTRACT Multiple sclerosis (MS) is a complex, multifactorial neurodegenerative disease with an aetiology that is still partially elusive. Several risk factors are associated with MS development including genetic predisposition and various environmental stressors; however, recently, viral infections have gained significant attention as a crucial ...
Samanta Plavina +11 more
wiley +1 more source
Is Magnetic Reconnection Dominantly Spatially or Temporally Variable: First Results From TRACERS
Journal of Geophysical Research: Space Physics, Volume 131, Issue 11, November 2026.Abstract The Tandem Reconnection And Cusp Electrodynamics Reconnaissance Satellites (TRACERS) small explorer mission was designed to: Determine whether magnetopause reconnection is primarily spatially or temporally variable for a range of solar wind conditions. Observations from the Analyzers for Cusp Ions (ACIs) on the two TRACERS spacecrafts are used
S. A. Fuselier +22 more
wiley +1 more source
Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 11, Page 1819-1830, November 2026.Anumigilimab, a novel anti‐G‐CSF receptor antibody, was investigated in a phase 1b trial involving 39 patients with hidradenitis suppurativa or palmoplantar pustulosis. No serious safety concerns related to anumigilimab were noted, and PK and PD were dose dependent.
Johannes S. Kern +14 more
wiley +1 more source