Results 141 to 150 of about 28,431 (214)

Targeting the KAT7/H3K14ac/RAC2 Axis Mediates OXPHOS to Promote Stemness Maintenance and Malignancy in Glioblastoma

Advanced Science, EarlyView.
SOX2 upregulates KAT7 in glioma stem cells, where KAT7 deposits H3K14 acetylation at the RAC2 promoter to activate RAC2 transcription. RAC2‐GTP subsequently promotes PAK1/2/3 phosphorylation, increasing tricarboxylic acid cycle flux and mitochondrial respiration to support glioblastoma malignancy.
Jilong Liu, Yanfei Sun, Yuehua Zhu, Guangjing Mu, Jiazheng Wang, Liangliang Wang, Feihu Zhao, Zhimin Zhao, Jian Wang, Ying He, Zheng Jiang, Xingang Li, Mingzhi Han, Bin Huang   +13 more
wiley   +1 more source

An Integrated Photo-Magnetic Sensor Chip Using Giant Magnetoresistance (GMR) and Light-Dependent Resistor (LDR) Technologies Based on Microfabrication Compatibility. [PDF]

Micromachines (Basel)
Sun X, Chen X, Li J, Ren C, Tian T, Guo A, Lei C.   +6 more
europepmc   +1 more source

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

Advanced Science, EarlyView.
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen, Ying Ma, Lixuan Huang, Xin Chen, Fanliang Kong, Zhenzhou Qian, Mingyue Guan, Xinlin Wang, Yanyan Yang, Shasha Zhang, Peng Li, Renjie Chai   +11 more
wiley   +1 more source

Observing strong optical nonreciprocity from magnetically doped Dirac semimetals. [PDF]

Nat Commun
Nabavi B, Jafari Ghalekohneh S, Ness H, Pashov D, van Schilfgaarde M, Leahy I, Rice A, Norman A, Alberi K, Zhao B.   +9 more
europepmc   +1 more source

Targeting the CRYAB/β‐Catenin Axis with an MMP‐9‐Responsive Hydrogel Disrupts CTC Clusters to Suppress Progression of Hepatocellular Carcinoma after Radiofrequency Ablation

Advanced Science, EarlyView.
The graphical abstract illustrates that sublethal thermal stress after iRFA upregulates the chaperone CRYAB in residual HCC cells, which stabilizes β‐catenin and drives a dual pathological program, including EMT and N2‐TAN polarization, thereby leading to heterotypic CTC cluster formation. The MMP‐9‐responsive hydrogel (XB@Gel) delivers XAV‐939 and BMS‐
Hui Chen, Danni Yang, Songying Pi, Yuhan Liu, Hongbin Huang, Feile Ye, Yuhong Lin, Zhongzhen Su, Yongquan Huang   +8 more
wiley   +1 more source

Self‐Sustaining Sensing Systems: Integration Strategies and Signal–Power Matching in Energy‐Harvesting Electronics

Advanced Science, EarlyView.
Energy‐harvesting‐integrated sensors couple ambient energy conversion with sensing, processing, and wireless communication. This review organizes recent progress through integration architectures and operating principles, revisiting co‐packaged, monolithic, and co‐functional designs together with always‐on, event‐driven, and multi‐modal sensing modes ...
Taehyun Park, Ki‐Yoon Park, Yeonho Choi, Dong‐Myeong Shin, Hong‐Joon Yoon, Hocheon Yoo   +5 more
wiley   +1 more source

High Spin Manganese Boosting Photo-Magnetic Catalytic Hydrogen Evolution Over Covalent Organic Frameworks. [PDF]

Adv Mater
Zhou L, Yan T, Sun A, Fan Z, Li S, Ding X, Yang Y, Dai K, Chai B, Wang S, Zhang X, Chen H.   +11 more
europepmc   +1 more source

Cross‐scale Material‐Structure Synergy for 2D Metamaterials: Toward Customizable Intelligent Electromagnetic Manipulation in Multiphysics Fields

Advanced Science, EarlyView.
Recent advances in metasurface‐enabled low‐observable technologies are reviewed from the perspective of cross‐scale material–structure synergy. Electromagnetic, thermal, optical, and acoustic stealth are highlighted together with dynamic tuning, programmable coding, data‐driven inverse design, artificial intelligence, multispectral compatibility, and ...
Shuhao Wang, Xing Yang, Liping Liu, Yang Peng, Yangyang Wang, Hualiang Lv   +5 more
wiley   +1 more source

Light-induced bimerons in a chiral magnet. [PDF]

Nat Commun
Zhu K, Rybakov FN, Wang Z, Gao W, Sun S, Wang W, Li J, Tian H, Eriksson O, Yang H, Zhang Y, Kiselev NS, Li Z, Li J.   +13 more
europepmc   +1 more source

Volatile Additives Engineering: A Trustworthy Morphology Control Strategy in Non‐Fullerene Organic Solar Cells

Advanced Science, EarlyView.
In this review, the classification and development history of the volatile solid and solvent additives are comprehensively summarized, the underlying mechanisms of morphology optimization are discussed, and a summary of volatile additive‐induced improvements in interfacial layer performance is provided.
Jianqiang Qin, Zhiqin Lai, Jiang‐Ling Shi, Zheng Xiao, Yuwei Duan, Zhiping Hu, Juan Du, Qiang Peng   +7 more
wiley   +1 more source