Results 41 to 50 of about 273,761 (240)
Aberrant Splicing Signatures Underpin Oligodendrocyte Damage in ALS and Neuron Loss in FTD
Advanced Science, EarlyView.Integrating bulk and single‐nucleus RNA‐seq from ALS and FTD patients, we revealed distinct cellular dysfunctions, with severe oligodendrocyte damage in ALS and pronounced neuron loss in FTD. We identified cell‐type‐specific aberrant splicing events as potential biomarkers with robust classification performance, some of which produce de novo peptides ...
Chen Du +6 more
wiley +1 more source
Redox Biology, 2019 Recent clinical trials reported that increasing high-density lipoprotein-cholesterol (HDL-C) levels does not improve cardiovascular outcomes. We hypothesize that HDL proteome dynamics determine HDL cardioprotective functions.
Yuling Zhang +12 more
doaj +1 more source
Megalithic structures and dolmen orientation in Bulgaria [PDF]
Archaeoastronomy and Ancient Technologies, 2013 A review of the main types of megalithic and quasi-megalithic monuments in Bulgaria is presented together with maps of their localization. A large and modern data base about the orientation of 110 Thracian dolmens (XII-VII c. BC) is interpreted in detail.
Tsonev, L.V., Kolev, D.Z.
doaj +1 more source
Astronomical Calendar and Restoration Design of Clepsydra in the Silla era [PDF]
Journal of Astronomy and Space Sciences, 2008 We study on the astronomical calendars that was used in the Silla era. The calendars are deduced from the records in Samguksagi. They were influenced from calendaric system of Tang Dynasty, which are Lin duk calendar(?), Ta yen calendar(?) and Sun myung ...
Yong Sam Lee +3 more
doaj +1 more source
SEISMIC STUDY OF MODHERA SUN TEMPLE
International Journal of Research in Engineering and Technology, 2014 Monuments have been created for thousands of years, and they are often the most durable and famous symbols of ancient civilizations. They have witnessed many earthquakes with ominously less damage. The purpose of this project is to analyze the static and dynamic properties of ancient Indian monuments.
openaire +1 more source
Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy
Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley +1 more source
InfoMat, EarlyView.Two‐dimensional MA2Z4 such as MoSi2N4 offer a new path to extend transistor scaling beyond the limits of silicon. Due to their exceptional properties, these 2D semiconductors are promising candidates for future Ångström‐scale CMOS technology. This review outlines the computational design and roadmap bridging materials discovery, device design and ...
Che Chen Tho +11 more
wiley +1 more source
Biochemical basis and metabolic interplay of redox regulation
Redox Biology, 2019 Accumulated evidence strongly indicates that oxidative stress, characterized by an imbalance between reactive oxygen species (ROS) production and antioxidants in favor of oxidants, plays an important role in disease pathogenesis.
Lixiao Zhang +9 more
doaj +1 more source
Acta Biochimica et Biophysica Sinica, 2021 Since the first reported case in December of 2019, the coronavirus disease 2019 (COVID-19) has became an international public health emergency. So far, there are more than 228,206,384 confirmed cases including 4,687,066 deaths.
Xu Chuanming, Chen Yanting, Yu Jun
doaj +1 more source
Land Degradation &Development, EarlyView.ABSTRACT Clarifying the relationship between the supply and demand of recreation service not only enhances our comprehension of how cultural ecosystem services impact human well‐being, but also offers a theoretical foundation and scientific basis for developing regional landscape management strategies.
Xinyu Huang +5 more
wiley +1 more source