Age-Related Decline in Dendritic Architecture of Hippocampal CA1 Principal Neurons in a Mouse Model of Fragile X Syndrome. [PDF]
ABSTRACT Fragile X syndrome (FXS) is the most common inherited cause of intellectual disability and is associated with attention deficits, hyperactivity, anxiety, impulsivity, and repetitive behaviors. The disorder results from transcriptional silencing of the FMR1 gene, leading to loss of fragile X messenger ribonucleoprotein (FMRP), an RNA‐binding ...
Farooqi NNU, Nyengaard JR, Banke TG.
europepmc +2 more sources
Neurofunctional Correlates of Emotional Dysregulation: Systematic Review and ALE Meta-Analysis. [PDF]
ABSTRACT Background Emotional dysregulation (ED) is a transdiagnostic feature of several psychiatric and neurodevelopmental disorders, characterized by heightened emotional reactivity, mood instability, and difficulties regulating emotional responses.
Wong E +10 more
europepmc +2 more sources
Obstructive sleep apnoea is associated with accelerated progression of diabetic kidney disease. [PDF]
Abstract Aim Persons with type 2 diabetes and diabetic kidney disease (DKD) are at high risk of end‐stage kidney disease or death. We investigated the possible contribution of obstructive sleep apnoea (OSA) to decline in kidney function and renal outcomes.
Nielsen S +9 more
europepmc +2 more sources
Dette temanummer handler om ulighed i sundhed, og gennem syv meget for- skellige artikler sætter nummerets forfattere fokus på, hvordan ulighed i sund- hed kan opleves og forstås i dagens Danmark.
Bagge Bjerge +2 more
doaj +3 more sources
Patient Safety Climate in Danish Primary Care: Adaption and Validation of the Danish Safety Attitudes Questionnaire (SAQ-DK-PRIM) [Response to Letter] [PDF]
Marie Haase Juhl,1,2 Anne Estrup Olesen,1,2 Ellen Tveter Deilkås,3 Niels Henrik Bruun,4 Kirsten Høgh Obling,5 Nikoline Rytter,6 Maya Damgaard Larsen,6 Solvejg Kristensen7 1Department of Clinical Pharmacology, Aalborg University Hospital ...
Juhl MH +7 more
doaj +2 more sources
Difference in pre- and postnatal prevalence of congenital cardiac tumors in a large population-based cohort. [PDF]
Ultrasonic assessment of a large, contemporary cohort in Copenhagen, Denmark, revealed a prevalence of congenital cardiac tumors of 0.002% prenatally (gestational Weeks 18–21) and 0.027% postnatally. All cardiac tumors were located in the ventricles.
Sillesen AS +9 more
europepmc +2 more sources
Bevacizumab in ovarian cancer: Clinical data and predictive and prognostic biomarkers. [PDF]
Evidence supporting bevacizumab in ovarian cancer and predictive biomarkers: highlighting opportunities to improve patient selection and advance personalised treatment strategies. Abstract Angiogenesis, driven by the vascular endothelial growth factor (VEGF)/VEGFR signalling axis under hypoxic conditions, is one of the hallmarks of ovarian cancer (OC),
Lamia MR +6 more
europepmc +2 more sources
Internal consistency and construct validity of the Short Musculoskeletal Function Assessment (SMFA) in older adults [PDF]
Objective The primary objectives of this study were to 1) investigate the internal consistency 2) and construct validity of the Short Musculoskeletal Function Assessment Questionnaire (SMFA) in older adults commencing physical rehabilitation in an ...
Sanel Teljigovic +5 more
doaj +2 more sources
Gymnasieelevers sundhed som sanselige, kollektive og kropspolitiske engagementer
Artiklen undersøger gymnasieunges oplevelser med, forståelser af og praksisser omkring sundhed i deres hverdagsliv. Børn og unge eksponeres i dag for sundhedsbudskaber, påbud og overvågning i mange af de sociale sfærer med sundhed forstået som et ...
Kathrine Vitus
exaly +3 more sources
Influence of ethnicity on the diagnostic accuracy of plasma p-tau217 for the identification of Alzheimer's disease: A consecutive mixed memory clinic cohort study. [PDF]
Abstract INTRODUCTION Blood‐based biomarkers have demonstrated high accuracy for identifying Alzheimer's disease (AD) pathology. However, the lack of representative cohorts creates a knowledge gap regarding their real‐world applicability. We examined the influence of ethnicity on the diagnostic accuracy of plasma tau phosphorylated at threonine 217 (p ...
Kjaergaard D +9 more
europepmc +2 more sources

