Results 91 to 100 of about 1,956,285 (237)

From Molecular Targets to Advanced Delivery Systems: Aptamers for Precision Ocular Therapeutics

Advanced Therapeutics, Volume 9, Issue 10, October 2026.
Aptamer‐based strategies are revolutionizing ocular disease management through highly specific molecular recognition of disease specific molecular targets. This review systematically integrates therapeutic aptamer sequences, diagnostic aptasensor platforms, and targeted delivery strategies, highlighting design principles, ocular bioavailability ...
Minal Thacker, Ka‐Ying Wong, Liping Zhou, Man‐Sau Wong, Juewen Liu   +4 more
wiley   +1 more source

Nanoprobe‐Enabled Precision Imaging and Panoramic Boundary Delineation in Retinoblastoma

Cancer Innovation, Volume 5, Issue 5, October 2026.
This review highlights that nanoprobe‐enabled multimodal imaging, combined with targeted probe design and AI‐assisted analysis, significantly enhances the precise visualization and boundary delineation of retinoblastoma. It further outlines key challenges and directions for translating high‐performance imaging nanoprobes into clinical practice.
Xuefei He, Precious Amarachi Ikwuagwu, Wenjing Pang, Aomen Chen, Lingchao Xiang, Feng Chen, Chen Xu, Aiguo Wu   +7 more
wiley   +1 more source

Ionospheric electron content at temperate latitudes during the declining phase of the sunspot cycle [PDF]

, 1966
Ionospheric electron density during declining phase of sunspot cycle by Faraday effect ...
Flaherty, B. J., Yeh, K. C.
core  

Spot cycle reconstruction: an empirical tool:Application to the sunspot cycle

, 2015
Context. The increasing interest in understanding stellar magnetic activity cycles is a strong motivation for the development of parameterized starspot models which can be constrained observationally.Aims.
Cunha, M. S., A. R. G. Santos, M. S. Cunha, Avelino, P. P., P. P. Avelino, T. L. Campante, Santos, A. R. G., Campante, T. L.   +7 more
core   +1 more source

Predicting Geomagnetic Activity in the Ascending and Declining Phases of the Solar Cycle

Space Weather
Most predictions of space climate, that is, the long‐term behavior of the solar‐terrestrial environment, have focused on forecasting the 11‐year sunspot cycle.
Timo Qvick, Timo Asikainen, Kalevi Mursula   +2 more
doaj   +1 more source

Statistical study of the equatorial F2 layer critical frequency at Ouagadougou during solar cycles 20, 21 and 22, using Legrand and Simon’s classification of geomagnetic activity

Journal of Space Weather and Space Climate, 2012
This paper presents the statistical analysis of the diurnal variations of the F layer at the equatorial station of Ouagadougou (Lat: 12.4° N; Long: 358.5° E; dip: 5.9°) from 1966 to 1998 (=> ~11 680 days).
Amory-Mazaudier Christine, Ouattara Frédéric   +1 more
doaj   +1 more source

Investigation of HZE particle fluxes as a space radiation hazard for future Mars missions

Heliyon, 2019
Manned Mars missions planned in the near future of very low solar activity period and hence higher than acceptable radiation doses due mainly to the Galactic Cosmic Rays (GCR), would require special techniques and technological development for ...
Nagaraja Kamsali, S.C. Chakravarty, Praveen Kumar Basuvaraj   +2 more
doaj   +1 more source

Multimodal Characterization of APOE ε4‐Associated Neurovascular Heterogeneity Using Retinal, Plasma, and Neuroimaging Biomarkers in Alzheimer's Disease

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
The LASSO and logistic regression model integrate neuroimaging measures and retinal vascular biomarkers to identify key predictors of APOE ε4 status, improving genotype‐specific stratification. The model's calibration curve and decision curve analysis demonstrate improved discrimination and clinical utility when retinal vascular data are integrated ...
Haoran Cheng, Huwei Xia, Youjie Wang, Le Cao, Suqing Hu, Huayan Wang, William Robert Kwapong, Zhen Wang, Caiyun Wen   +8 more
wiley   +1 more source

Chromospheric seismology above sunspot umbrae [PDF]

, 2015
Context: The acoustic resonator is an important model for explaining the three-minute oscillations in the chromosphere above sunspot umbrae. The steep temperature gradients at the photosphere and transition region provide the cavity for the acoustic ...
G. J. J. Botha, B. Snow, Snow, Ben, Botha, Gert, Regnier, Stephane, S. Régnier   +5 more
core   +1 more source

Molecular and Cellular Underpinnings of Primary Hypertension: An Integrative Mechanistic Framework

Journal of Cellular Physiology, Volume 241, Issue 10, October 2026.
ABSTRACT Hypertension is a highly prevalent clinical condition and a major contributor to global cardiovascular morbidity and mortality. Despite extensive research, its complex and multifaceted pathogenesis is yet to be fully elucidated. This paper explores the updated understanding of primary hypertension as a systemic disorder rather than an isolated
Dima Nasrallah, Alaa Abdelhamid, Omar Tluli, Yaman Al‐Haneedi, Mera Abu Hussien, Ali H. Eid   +5 more
wiley   +1 more source