Results 101 to 110 of about 236,552 (310)

DifAugGAN: A Practical Diffusion-style Data Augmentation for GAN-based Single Image Super-resolution [PDF]

, 2023
Axi Niu, Kang Zhang, Joshua Tian Jin Tee, Trung X. Pham, Jinqiu Sun, Chang D. Yoo, In So Kweon, Yanning Zhang   +7 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Super-Resolution of Magnetic Resonance Images via Convex Optimization with Local and Global Prior Regularization and Spectrum Fitting

International Journal of Biomedical Imaging, 2018
Given a low-resolution image, there are many challenges to obtain a super-resolved, high-resolution image. Many of those approaches try to simultaneously upsample and deblur an image in signal domain.
Naoki Kawamura, Tatsuya Yokota, Hidekata Hontani   +2 more
doaj   +1 more source

Heterogeneity in extracellular vesicle secretion by single human macrophages revealed by super‐resolution microscopy

, 2022
Susanne Dechantsreiter, Ashley Ambrose, Jonathan D. Worboys, Joey Ming Er Lim, Sylvia Liu, Rajesh Shah, M. A. Montero, Anne Marie Quinn, Tracy Hussell, Gillian M. Tannahill, Daniel M. Davis   +10 more
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Guided Texture Transfer Network for Mid-Infrared Satellite Image Super Resolution

IEEE Access
Mid-infrared (MIR) satellite imagery captures thermal information and supports a wide range of remote sensing applications. However, its inherently low spatial resolution limits its utility for detailed spatial analysis.
Yeji Jeon, Youkyung Han, Kwang-Jae Lee, Yeseul Kim, Hanul Kim   +4 more
doaj   +1 more source

A double transformer residual super-resolution network for cross-resolution person re-identification

, 2023
Fuzhen Zhu, Ce Sun, Chen Wang, Bing Zhu
openalex   +1 more source

Simulation-based Lidar Super-resolution for Ground Vehicles [PDF]

, 2020
Tixiao Shan, Jinkun Wang, Fanfei Chen, Paul Szenher, Brendan Englot   +4 more
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source