Results 131 to 140 of about 2,430,403 (309)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Super Resolution and Deblurring of Hyperpanoramic Images Using Neural Networks

open access: yes
reservedIn this thesis we studied the application of Deep Neural Networks to the problem of Super Resolution of images, which consists in enhancing their spatial resolution and perceptual quality; we focused on images captured by a hyperpanoramic lens ...
BARBIERATO, MARCO
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Learning spectral and spatial features based on generative adversarial network for hyperspectral image super-resolution

open access: yes, 2019
Super-resolution (SR) of hyperspectral images (HSIs) aims to enhance the spatial/spectral resolution of hyperspectral imagery and the super-resolved results will benefit many remote sensing applications.
Lei Zhang (38117)   +6 more
core   +3 more sources

Neuromorphic Imaging With Super-Resolution

open access: yesIEEE Transactions on Circuits and Systems for Video Technology
Neuromorphic imaging is an emerging technique that imitates the human retina to sense variations in dynamic scenes. It responds to pixel-level brightness changes by asynchronous streaming events and boasts microsecond temporal precision over a high dynamic range, yielding blur-free recordings under extreme illumination.
Pei Zhang   +4 more
openaire   +2 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

open access: yesFEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson   +2 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

A mathematical theory of super-resolution and two-point resolution

open access: yesForum of Mathematics, Sigma
This paper focuses on the fundamental aspects of super-resolution, particularly addressing the stability of super-resolution and the estimation of two-point resolution. Our first major contribution is the introduction of two location-amplitude identities
Ping Liu, Habib Ammari
doaj   +1 more source

Super-resolution enhancement by quantum image scanning microscopy

open access: yes, 2018
The principles of quantum optics have yielded a plethora of ideas to surpass the classical limitations of sensitivity and resolution in optical microscopy.
Alexander Krupinski-Ptaszek (15945413)   +7 more
core   +1 more source

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