Results 71 to 80 of about 1,684,691 (312)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

A Lightweight Reconstruction Model via a Neural Network for a Video Super-Resolution Model

open access: yesApplied Sciences, 2023
Super-resolution in image and video processing has been a challenge in computer vision, with its progression creating substantial societal ramifications.
Xinkun Tang   +3 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Biotin methyl ester enhances cargo release in RUSH system and enables rapid biotinylation with TurboID

open access: yesCommunications Biology
Biotin-streptavidin technology is a key tool in biotechnology. The engineering of streptavidin or streptavidin-like molecules and organic synthesis of biotin derivatives offer a variety of applications to meet the needs of researchers.
Taisei Uehara   +7 more
doaj   +1 more source

Deciphering the sub-Golgi localization of glycosyltransferases via 3D super-resolution imaging

open access: yesCell Structure and Function
The Golgi apparatus, a crucial organelle involved in protein processing, including glycosylation, exhibits complex sub-structures, i.e., cis-, medial, and trans-cisternae.
Hirokazu Yagi   +11 more
doaj   +1 more source

Iterative Back Projection Network Based on Deformable 3D Convolution

open access: yesIEEE Access, 2023
Video super-resolution technology enhances the display quality of videos by obtaining high-resolution videos from low-resolution videos. Unlike single-image super-resolution, utilizing information between adjacent video frames is crucial in video super ...
Chengzhi Luo, Bing Li, Feng Liu
doaj   +1 more source

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

Super-Resolution Raman Spectroscopy by Digital Image Processing

open access: yesJournal of Spectroscopy, 2013
We demonstrate the results of a strain (stress) evaluation obtained from Raman spectroscopy measurements with the super-resolution method (the so-called super-resolution Raman spectroscopy) for a Si substrate with a patterned SiN film (serving as a ...
Motohiro Tomita   +5 more
doaj   +1 more source

Shedding Structured Light on Molecular Immunity: The Past, Present and Future of Immune Cell Super Resolution Microscopy

open access: yesFrontiers in Immunology, 2021
In the two decades since the invention of laser-based super resolution microscopy this family of technologies has revolutionised the way life is viewed and understood.
Timothy M. Johanson   +5 more
doaj   +1 more source

Super-resolution imaging within reach

open access: yes, 2018
Although several optical techniques have been recently developed in order to overcome the resolution limit in microscopy, the imaging of sub-wavelength features is still a real challenge. In practise, super-resolution techniques remain difficult to build
Sylvain Lecler (11065068)   +3 more
core   +1 more source

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