Objective: The aim of the present investigation was to design and evaluate orally disintegrating tablet (ODT) of Ibuprofen, a NSAID drug used for the treatment of arthritis with a view to improve its oral bioavailability. The focus of the current study was to develop ODT of Ibuprofen using super disintegrants for ease of administration and its ...
Hrishav Das Purkayastha, Nath Bipul
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Impact of physicochemical environment on the super disintegrant functionality of cross-linked carboxymethyl sodium starch: insight on formulation precautions. [PDF]
Delalonde M +4 more
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Formulation and In-Vitro Evaluation Studies on Oral Disintegration Tablets of Antiulcer Using Super Natural Disintegrants [PDF]
The demand for orally disintegrating tablets (ODT) has been growing the last decade especially for elderly and children who have swallowing difficulties The present study focuses on the formulation and evaluation of orally disintegrating tablets (ODTs) for the treatment of ulcers, utilizing a super natural disintegrant..
Arti Bhagat +3 more
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This study developed a sustainable super-disintegrant derived from Dioscorea hispida Dennst. var. hispida starch for use in immediate-release pharmaceutical tablets.
Nuntachai Hanpramukkun +4 more
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Development and Evaluation of MCC-SiO2/CMC-SiO2 Conjugates as Tablet Super-Disintegrants. [PDF]
In the present study, microcrystallinecellulose–colloidal silicon dioxide (MCC-SiO2) and carboxymethylcellulose–colloidal silicon dioxide (CMC-SiO2) conjugates have been investigated as superdisintegrants in fast dissolving tablets (FDTs). MCC-SiO2 and CMC-SiO2 conjugates were prepared and micromeritic studies, FTIR, SEM and XRD methods were utilized ...
Sangnim T +5 more
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Formulation and Evaluation of Roxithromycin Dispersible Tablets Using Super Disintegrants
Dispersible tablets of Roxithromycin were prepared using a superdisintegrant such as Primogel powder, Kollidone powder, Crosscaramellose powder , and MCC in different concentration by direct compression method. Formulations were evaluated for the standard of dispersible tablets . It was observed that all the formulations were acceptable with reasonable
Ms.Subhasri Mohapatra
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A Review on Formulation and pharmacological activity assessment of Oral Disintegration Tablets of Antiulcer Using Super Natural Disintegrant [PDF]
Orally disintegrating tablets (ODTs) have gained significant attention in the pharmaceutical industry due to their convenience, especially for patients with dysphagia, pediatric, and geriatric populations. The formulation of antiulcer ODTs using super natural disintegrants is a novel approach aimed at improving drug dissolution, bioavailability, and ...
AHMAD LOUIS +2 more
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Natural Super-Disintegrant Agents Used in Various Oral Solid Dosage Forms
Super-disintegrating agents are one of the ingredients used in pharmaceutical solid dosage forms. These substances play a vital role in formulation design. Natural super-disintegrants have gained more popularity due to their oral bioavailability. It disintegrates the tablets into smaller particles to enhance the dissolution rate.
V.T. Iswariya +3 more
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The main aim of the present research was to develop a fast dissolving oral polymeric film with good mechanical properties, faster disintegration and dissolution when placed on tongue. Donepezil hydrochloride (DPH) is prescribed in the treatment of mild to moderate Alzheimers disease (AD). The polymers selected for preparing films were sodium alginate (
P K Lakshmi, D.R. Lavanya, Misha Ali
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Comprehensive Review of Oro Dispersible Tablets and Co Processed Super disintegrants
Due to their ease of administration, self-administration, and improved patient compliance, solid dosage forms are most popular. The most normally utilized strong dose structures are tablets and capsules, which is challenging for pediatric and geriatric patients. Considering these prerequisites endeavors have been made to foster rapid dissolving Tablets.
Voleti Vijaya Kumar +6 more
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