Results 41 to 50 of about 1,733 (227)

Novel polyvinylpyrrolidones to improve delivery of poorly-water soluble drugs; from design to synthesis and evaluation [PDF]

, 2012
Polyvinylpyrrolidone is a widely used in tablet formulations with the linear form acting as a wetting agent and disintegrant whereas the cross-linked form is a super-disintegrant.
Chappell, David, Greenland, Barnaby W, Hayes, Wayne, Khutoryanskaya, Olga, Niemczyk, Anna I, Rawlinson-Malone, Clare F, Timmins, Peter, Williams, Adrian C   +7 more
core   +1 more source

The use of high performance anion exchange chromatography for the detection of counterfeit pharmaceutical products using the excipient content as a marker [PDF]

, 2015
The aim of the investigation described here was to examine the differences between genuine and counterfeit pharmaceutical products through the development of an analytical method capable of rigorously identifying the sugar-based excipients.
Beasley, Emma, Coleman, Tyler, Suman, Mandeesh   +2 more
core   +2 more sources

Design, formulation, and physicochemical evaluation of montelukast orally disintegrating tablet

International Journal of Preventive Medicine, 2016
Background: Orally disintegrating tablets (ODTs) are a modern form of tablets that when placed in the oral cavity, disperses rapidly. These tablets have advantages, particularly good applications for children and old patients who have a complication in ...
Abolfazl Aslani, Maryam Beigi
doaj   +1 more source

Formulation, in vitro characterization and optimization of taste-masked orally disintegrating co-trimoxazole tablet by direct compression.

PLoS ONE, 2021
IntroductionOrally disintegrating tablet (ODT) is a dosage form that overcomes the problem of swallowing which is prevalent in about 35% of the general population.
Chernet Tafere, Zewdu Yilma, Solomon Abrha, Adane Yehualaw   +3 more
doaj   +1 more source

Crystal engineering of ibuprofen using starch derivatives in crystallization medium to produce promising ibuprofen with improved pharmaceutical performance [PDF]

, 2015
Ibuprofen exhibits poor flow, poor compaction and dissolution behaviour, and it is prone to capping after ejection from the die. Therefore, the aim of the present research was to engineer ibuprofen crystals in the presence of two disintegrants (starch ...
Amaro-González, Bansal, Bolhuis, Bos, Bumiller, Carr, Carr, Chow, Chowdary, Edge, Fu, Garekani, Gordonx, Hannula, Hendriksen, Homayouni, Homayouni, Jallo, Kaialy, Kaul, Kenji, Khan, Kottke, Kottke, Levy, Maghsoodi, Maghsoodi, Nada, Nikolakakis, Nokhodchi, Nokhodchi, Nokhodchi, Nokhodchi, Podczeck, Prasad, Raghavan, Rasenack, Rasenack, Rasenack, Roberts, Sadeghi, Seton, Sun, Swain, Udupa, Wells, York   +46 more
core   +1 more source

Formulation Development, Evaluation and Comparative Study of Effects of Super Disintegrants in Cefixime Oral Disintegrating Tablets [PDF]

Journal of Young Pharmacists, 2010
The present work was aimed at formulation development, evaluation and comparative study of the effects of superdisintegrants in Cefixime 50 mg oral disintegrating tablets. The superdisintegrants used for the present study were sodium starch glycolate and crosscarmellose sodium.
Remya, KS, Beena, P, Bijesh, PV, Sheeba, A   +3 more
openaire   +2 more sources

Formulation, characterization, and evaluation of orodispersible tablet of a model antidepressant drug

Indian Journal of Health Sciences and Biomedical Research KLEU, 2016
Introduction: Paroxetine hydrochloride is used as the antidepressant drug of the selective serotonin reuptake inhibitor. It is used to treat depression resistant to other antidepressants, depression complicated by anxiety, panic disorder, obsessive ...
V G Jamakandi, Chetan Prakash Kalsannavar, S P Hiremath, F S Dasanakoppa, S S Kerur   +4 more
doaj   +1 more source

Fast disintegrating crystalline solid dispersions of simvastatin for incorporation into orodispersible tablets [PDF]

, 2014
Aim : Spray dried solid dispersion (SDP) of crystalline simvastatin (SIM) in a fast disintegrating matrix of superdisintegrants was studied as a method to enhance SIM dispersibility, rheology, compactibility and compressibility for incorporation into ...
Ambike, Broadhead, Chowdary, De, Doelker, Frizon, Fu, Goddeeris, Gonnissen, Joiris, Jun, Kang, Margulis-Goshen, Moneghini, Mukharya, Pabari, Pabari, Patel, Puttipipatkhachorn, Ramtoola, Rytting, Sareen, Sharma, Shi, Simões, Whiteman, Yang, Yen, Yoshinari, Yu, Zimper   +30 more
core   +2 more sources

Synthesis and Physicochemical Characterization of Banana Starch Tartrate and its Application as Disintegrant in Telmisartan Tablets [PDF]

, 2020
The present investigation was aimed to isolate banana starch (BS), synthesis of banana starch tartrate (BST), characterization, and application as a novel disintegrant in telmisartan tablets.
Chaudhary, Rekhadevi H., Kartan, Sonam B., Khandagale, Prakash D., Puri, Abhijeet Vishnu, Tiwari, Ankita U.   +4 more
core   +2 more sources

FORMULATION AND EVALUATION OF ORODISPERSIBLE ATENOLOL MALEATE TABLETS: A COMPARATIVE STUDY ON NATURAL SUPER DISINTEGRENTS AND SYNTHETIC SUPER DISINTEGRENTS

INTERNATIONAL JOURNAL OF RESEARCH IN AYURVEDA & PHARMACY, 2014
O ral Disintegrating T ablets (ODT s ) may also be used to deliver drugs to the oral cavity, for local action or, in some cases, absorption across the oral mucosa, thereby avoiding first - pass hepatic metabolism and po tentially increasing the rate and extent of uptake, and reducing undesirable metabolites. The o bjectives of the research work wa s to
Brahmaiah Bonthagarala, Prasanth Pasumarthi, Katta Vamsi Kiran, Sathram Nataraja, Sudarshan Donthiboina   +4 more
openaire   +1 more source