Results 51 to 60 of about 1,733 (227)

Formulation and evaluation of gastro-retentive floating bilayer tablet for the treatment of hypertension

open access: yesHeliyon, 2020
The paper aimed to progress an ideal gastro retentive drug delivery system intended for directing Losartan and Hydrochlorothiazide as a fixed-dose combination for anti-hypertensive therapy.
Balaji Maddiboyina   +10 more
doaj   +1 more source

Non-destructive determination of disintegration time and dissolution in immediate release tablets by terahertz transmission measurements [PDF]

open access: yes, 2017
Purpose: The aim of this study was to establish the suitability of terahertz (THz) transmission measurements to accurately measure and predict the critical quality attributes of disintegration time and the amount of active pharmaceutical ingredient (API)
Goodwin, Daniel J.   +4 more
core   +1 more source

Design and evaluation of electrospun fibers for unidirectional buccal delivery of atorvastatin [PDF]

open access: yesPharmacia
This study focused on atorvastatin calcium trihydrate (ATV), which is characterized by low bioavailability due to high intestinal metabolism and the hepatic first-pass effect.
Zainab Farhan Muaiz   +1 more
doaj   +3 more sources

FORMULATION AND EVALUATION OF ORODISPERSIBLE TABLETS (ODTS) OF DICLOFENAC SODIUM BY USING SUPERDISINTEGRANT FROM NATURAL ORIGIN [PDF]

open access: yes, 2019
Objective: In this study, a polysaccharide isolated from the seeds of Cajanus cajan (pigeon pea) was investigated as a super disintegrant in the orodispersible tablets of diclofenac sodium.
BARATAM, SRINIVASA RAO   +3 more
core   +3 more sources

Formulation and evaluation of orodispersible Enalapril maleate tablets: a comparative study on natural super disintegrents and synthetic super disintegrents

open access: yesInternational Journal of Advances in Scientific Research, 2015
The aim of the present investigation is to formulate Enalapril maleate oral disintegrating tablet by using natural and synthetic superdisintegrents..ODTs may also be used to deliver drugs to the oral cavity, for local action or, in some cases, absorption across the oral mucosa, thereby avoiding first-pass hepatic metabolism and potentially increasing ...
Kameswara Rao.S   +5 more
openaire   +2 more sources

Chronomodulated drug delivery system of Irbesartan: Formulation and development using Desing of Experiment (DoE)

open access: yesBulletin of Faculty of Pharmacy Cairo University, 2018
The work is based on pulsatile principles to deliver a programmed dose of Irbesartan, an angiotensin-II receptor antagonist for chronotherapy of hypertension induced by excessive secretion of aldosterone, thereby lower the blood pressure at early morning.
Komal Parmar   +2 more
doaj   +1 more source

Formulation and Evaluation of Sumatriptan Succinate Oral Disintegrating Tablets Using Super Disintegrants

open access: yes, 2019
{"references": ["Rangasamy Manivannan. Oral disintegrating tablets: A future Compaction Publication International Journal of Pharmaceutical Research and Development 2009; 1: 1-10.", "https://pubchem.ncbi.nlm.nih.gov/compound/sumatriptan", "Mishra DN, Bindal M, Singh SK. Rapidly disintegrating oral tablet of valdecoxib. Indian drug.
Lakshmana Rao P   +5 more
openaire   +1 more source

Serial Chemical Crystallography for Autonomous Quantitative Phase Analysis in an Electron Microscope

open access: yesSmall Methods, Volume 9, Issue 12, December 1, 2025.
t‐SerialED, a novel electron diffraction method, enables rapid, high‐throughput structural analysis of nano‐sized materials. By adapting a batch‐by‐batch data collection approach, t‐SerialED integrates 3D reciprocal information to serial crystallography datasets.
Taimin Yang   +5 more
wiley   +1 more source

Evaluation of the ability of powdered milk to produce mini-tablets to deliver paracetamol in pediatrics [PDF]

open access: yes, 2015
Paper presented at the 7th International Granulation Workshop. 1-3 July 2015, University of Sheffield, UK"This work aims to evaluate the usefulness of powdered milk as a vehicle of drugs for direct compression into mini-tablets specifically designed for ...
Brachkova, Mariya   +3 more
core  

Therapeutic Oligonucleotides for Neurodegenerative Diseases: Aptamer Strategies and Clay Nanoparticle‐Based Delivery

open access: yesThe Chemical Record, Volume 25, Issue 10, October 2025.
This review explores aptamers as therapeutic oligonucleotides targeting neurodegenerative diseases, including Alzheimer's, Parkinson's, and Huntington's, with a focus on G‐quadruplex‐forming sequences. It discusses chemical modifications that enhance aptamer stability and function, alongside the use of clay nanoparticles, such as halloysite nanotubes ...
Valentina Arciuolo   +9 more
wiley   +1 more source

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