Results 61 to 70 of about 1,733 (227)

Formulation and development of orodispersible sustained release tablet of domperidone [PDF]

open access: yes, 2016
Commercially available domperidone orodispersible tablets (ODT) are intended for immediate release of the drug, but none of them have been formulated for sustained action.
Patil, Hemlata   +3 more
core   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

open access: yesAdvanced Functional Materials, Volume 35, Issue 35, August 28, 2025.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan   +4 more
wiley   +1 more source

Surface and Subsurface Mass Spectrometric Analysis of Dexamethasone in Solid Pharmaceutical Dosage Forms

open access: yesJournal of Mass Spectrometry, Volume 60, Issue 6, June 2025.
ABSTRACT This study presents an in‐depth mass spectrometric investigation of dexamethasone (DEX) distribution within pharmaceutical tablets using time‐of‐flight secondary ion mass spectrometry (ToF‐SIMS) combined with gas cluster ion beam (GCIB) sputtering.
Matjaž Finšgar
wiley   +1 more source

Use of seed gums from Tamarindus indica and Cassia fistula as controlled-release agents

open access: yesAsian Journal of Pharmaceutical Sciences, 2018
Most seed gums have been widely used in oral and topical pharmaceutical formulations, cosmetics, and food products because of their hydrophilic properties.
Kampanart Huanbutta   +1 more
doaj   +1 more source

QUALITY BY DESIGN (QBD) AS A TOOL FOR THE OPTIMIZATION OF INDOMETHACIN FREEZE-DRIED SUBLINGUAL TABLETS: IN VITRO AND IN VIVO EVALUATION [PDF]

open access: yes, 2021
Objective: This study aims to prepare and optimize indomethacin freeze-dried sublingual tablets (IND-FDST) by utilizing a quality by design (QbD) approach to achieve rapid drug dissolution and simultaneously bypassing the GIT for better patient ...
ELMAHDY ELSAYYAD, NIHAL MOHAMED   +3 more
core   +1 more source

A State‐of‐the‐Art Appraisal of Nanomaterials in Microneedles in the Delivery of Therapeutics and Vaccines

open access: yesAdvanced NanoBiomed Research, Volume 5, Issue 3, March 2025.
Nanomaterial‐integrated microneedles revolutionize transdermal delivery, enabling targeted and controlled administration of therapeutics and vaccines. This review explores advancements in design, manufacturing, and applications, emphasizing enhanced drug stability, bioavailability, and patient adherence. Key preclinical and clinical findings as well as
Bwalya Angel Witika   +3 more
wiley   +1 more source

Understanding the Effect of Diluents on Powder Flow and Tablet Properties of Poorly Compressible Black Pepper Extract Using Mixture Design Approach

open access: yesInternational Journal of Food Science, Volume 2025, Issue 1, 2025.
The application of black pepper extract in dietary supplement formulations is often limited by its inherently poor compressibility, which renders direct compression into tablets problematic. Therefore, the selection of appropriate diluents to enhance the compressibility of black pepper extract is essential.
Chaowalit Monton   +2 more
wiley   +1 more source

OPTIMISATION OF IBUPROFEN FAST DISSOLVING TABLETS EMPLOYING STARCH XANTHATE USING 23 FACTORIAL DESIGN [PDF]

open access: yes, 2017
Objective: To evaluate starch xanthate as a super disintegrant in the formulation of fast dissolving tablets of poorly soluble drugs employing 23 factorial design.Methods: Starch xanthate was synthesized by gelatinization process.
Kumar, R. Santosh   +2 more
core   +3 more sources

Application of poly(acrylic acid) superporous hydrogel microparticles as a super-disintegrant in fast-disintegrating tablets

open access: yesJournal of Pharmacy and Pharmacology, 2004
Abstract Poly(acrylic acid) superporous hydrogel (SPH) microparticles possessing a unique porous structure were used as a wicking agent to decrease disintegration time of fast-disintegrating tablets (FDTs). The compression behaviour of poly(acrylic acid) SPH microparticles was evaluated using the Kawakita equation. Effects of various SPH
Shicheng, Yang   +3 more
openaire   +2 more sources

A Study of Pharmaceutical Applications of Hemicelluloses From Nine Food Materials

open access: yesInternational Journal of Polymer Science, Volume 2025, Issue 1, 2025.
Objective: This study is aimed at evaluating the release‐extending, film‐coating, suspending, and thickening properties of various food‐derived hemicelluloses, as natural alternatives to synthetic excipients for use in pharmaceutical tablets and suspensions. Background: Hemicelluloses are partially digestible biopolymers with superior biocompatibility,
Irva Waqar   +6 more
wiley   +1 more source

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