Results 61 to 70 of about 1,733 (227)
Formulation and development of orodispersible sustained release tablet of domperidone [PDF]
Commercially available domperidone orodispersible tablets (ODT) are intended for immediate release of the drug, but none of them have been formulated for sustained action.
Patil, Hemlata +3 more
core +1 more source
Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan +4 more
wiley +1 more source
ABSTRACT This study presents an in‐depth mass spectrometric investigation of dexamethasone (DEX) distribution within pharmaceutical tablets using time‐of‐flight secondary ion mass spectrometry (ToF‐SIMS) combined with gas cluster ion beam (GCIB) sputtering.
Matjaž Finšgar
wiley +1 more source
Use of seed gums from Tamarindus indica and Cassia fistula as controlled-release agents
Most seed gums have been widely used in oral and topical pharmaceutical formulations, cosmetics, and food products because of their hydrophilic properties.
Kampanart Huanbutta +1 more
doaj +1 more source
QUALITY BY DESIGN (QBD) AS A TOOL FOR THE OPTIMIZATION OF INDOMETHACIN FREEZE-DRIED SUBLINGUAL TABLETS: IN VITRO AND IN VIVO EVALUATION [PDF]
Objective: This study aims to prepare and optimize indomethacin freeze-dried sublingual tablets (IND-FDST) by utilizing a quality by design (QbD) approach to achieve rapid drug dissolution and simultaneously bypassing the GIT for better patient ...
ELMAHDY ELSAYYAD, NIHAL MOHAMED +3 more
core +1 more source
Nanomaterial‐integrated microneedles revolutionize transdermal delivery, enabling targeted and controlled administration of therapeutics and vaccines. This review explores advancements in design, manufacturing, and applications, emphasizing enhanced drug stability, bioavailability, and patient adherence. Key preclinical and clinical findings as well as
Bwalya Angel Witika +3 more
wiley +1 more source
The application of black pepper extract in dietary supplement formulations is often limited by its inherently poor compressibility, which renders direct compression into tablets problematic. Therefore, the selection of appropriate diluents to enhance the compressibility of black pepper extract is essential.
Chaowalit Monton +2 more
wiley +1 more source
OPTIMISATION OF IBUPROFEN FAST DISSOLVING TABLETS EMPLOYING STARCH XANTHATE USING 23 FACTORIAL DESIGN [PDF]
Objective: To evaluate starch xanthate as a super disintegrant in the formulation of fast dissolving tablets of poorly soluble drugs employing 23 factorial design.Methods: Starch xanthate was synthesized by gelatinization process.
Kumar, R. Santosh +2 more
core +3 more sources
Abstract Poly(acrylic acid) superporous hydrogel (SPH) microparticles possessing a unique porous structure were used as a wicking agent to decrease disintegration time of fast-disintegrating tablets (FDTs). The compression behaviour of poly(acrylic acid) SPH microparticles was evaluated using the Kawakita equation. Effects of various SPH
Shicheng, Yang +3 more
openaire +2 more sources
A Study of Pharmaceutical Applications of Hemicelluloses From Nine Food Materials
Objective: This study is aimed at evaluating the release‐extending, film‐coating, suspending, and thickening properties of various food‐derived hemicelluloses, as natural alternatives to synthetic excipients for use in pharmaceutical tablets and suspensions. Background: Hemicelluloses are partially digestible biopolymers with superior biocompatibility,
Irva Waqar +6 more
wiley +1 more source

