Results 91 to 100 of about 871,767 (331)
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Statistical performance analysis of a fast super-resolution technique using noisy translations [PDF]
It is well known that the registration process is a key step for super-resolution reconstruction. In this work, we propose to use a piezoelectric system that is easily adaptable on all microscopes and telescopes for controlling accurately their motion ...
Chainais, Pierre, Leray, Aymeric
core
Multi-Contrast MRI Super-Resolution via a Multi-Stage Integration Network [PDF]
Chun-Mei Feng +3 more
openalex +1 more source
Suitability of Single Image Super Resolution Models for Video Super Resolution
This project is an attempt to understand the suitability of the Single image super resolution models to video super resolution. Super Resolution refers to the process of enhancing the quality of low resolution images and video. Single image super resolution algorithms refer to those algorithms that can be applied on a single image to enhance its ...
Shreyas D G +2 more
openaire +2 more sources
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
RudLOV is an optically synchronized cargo transport method revealing unexpected effects of dynasore
Live imaging of secretory cargoes is a powerful method for understanding the mechanisms of membrane trafficking. Inducing the synchronous release of cargoes from an organelle is key for enhancing microscopic observation.
Tatsuya Tago +7 more
doaj +1 more source
Accelerated CT Sub-pixel Super Resolution
The resolution of standard CT scans is dictated by the physical constraints of the detector’s sampling resolution. Super resolution is a class of techniques used to improve the reconstruction resolution beyond the physical limitations of the detector ...
Lucas Determan +2 more
doaj +1 more source
Guided Cascaded Super-Resolution Network for Face Image
The image super-resolution algorithm can overcome the imaging system's hardware limitation and obtain higher resolution and clearer images. Existing super-resolution methods based on convolutional neural networks(CNN) can learn the mapping relationship ...
Lin Cao +4 more
doaj +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source

