Results 111 to 120 of about 25,273 (241)

QCD on the BlueGene/L Supercomputer [PDF]

, 2005
Gyan Bhanot, D. Chen, Alan Gara, James Sexton, Pavlos Vranas   +4 more
openalex   +1 more source

Computational Evaluation of Statin Analogs Targeting HMG‐CoA Reductase for Coronary Artery Disease Treatment

ChemistryOpen, EarlyView.
Molecular dynamics analysis of novel statin analogs shows that binding induces superior stabilization of HMG‐CoA reductase. As shown by the solvent‐accessible surface area profile, ligand‐induced rigidity offers a new, effective strategy for drug design. Cardiovascular diseases remain a leading cause of global mortality.
Yoshua B. Mtulo, Geradius Deogratias, James E. Mgaya, Andrew S. Paluch, Lucas Paul   +4 more
wiley   +1 more source

Corrigendum: Extremely Scalable Spiking Neuronal Network Simulation Code: From Laptops to Exascale Computers

Frontiers in Neuroinformatics, 2018
Jakob Jordan, Tammo Ippen, Tammo Ippen, Moritz Helias, Moritz Helias, Itaru Kitayama, Mitsuhisa Sato, Jun Igarashi, Markus Diesmann, Markus Diesmann, Markus Diesmann, Susanne Kunkel, Susanne Kunkel   +12 more
doaj   +1 more source

Using Supercomputers to Speed Execution of the CAISO/PLEXOS 33% RPS Study

, 2011
C Meyers, Frederick H. Streitz, Yiming Yao, Steven M. Smith, A Lamont, Alan Lamont   +5 more
openalex   +2 more sources

American universities need greater access to supercomputers [PDF]

, 1984
G. Dallaire
openalex   +1 more source

Structural Modeling and Dynamics of the Full‐Length Homer1 Multimer

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Homer proteins are modular scaffold molecules that constitute an integral part of the protein network within the postsynaptic density. Full‐length Homer1 forms a large homotetramer via a long coiled coil region, and can interact with proline‐rich target sequences with its globular EVH1 domain.
Zsófia E. Kálmán, András Czajlik, Brigitta Maruzs, Fanni Farkas, István Pap, Csilla Homonnay, Tomas Klumpler, Gyula Batta, Zoltán Gáspári, Bálint Péterfia   +9 more
wiley   +1 more source

FatPaths: Routing in Supercomputers and Data Centers when Shortest Paths Fall Short [PDF]

, 2020
Maciej Besta, Marcel Schneider, Karolina Cynk, Marek Konieczny, Erik Henriksson, Salvatore Di Girolamo, Ankit Singla, Torsten Hoefler   +7 more
openalex   +1 more source

A regional implementation of a mixed finite‐element, semi‐implicit dynamical core

Quarterly Journal of the Royal Meteorological Society, EarlyView.
A regional version of a new dynamical core with an iterated semi‐implicit time discretisation and mixed finite‐element spatial discretisation is described. This involves modifying the mixed‐system and Helmholtz‐preconditioner equations to use lateral boundary condition (LBC) data specified by a driving model.
Christine Johnson, Ben Shipway, Thomas Melvin, Thomas Bendall, James Kent, Ian Boutle, Alex Brown, Mohamed Zerroukat, Benjamin Buchenau, Nigel Wood   +9 more
wiley   +1 more source

T2K Open Supercomputer and Industrial Use for Innovation

, 2009
Yutaka Ishikawa, Takahiro Katagiri, Tamotsu Yoshihiro   +2 more
openalex   +2 more sources

Improving convection‐permitting all‐sky infrared radiance ensemble data assimilation through mitigating deleterious non‐Gaussian artifacts

Quarterly Journal of the Royal Meteorological Society, EarlyView.
Ensemble Kalman filters (EnKFs) with quality control (QC) are commonly used in the data assimilation (DA) of all‐sky satellite‐sensed infrared radiance (IR) observations. However, the statistical assumptions underlying EnKFs and QC are violated in such DA.
Man‐Yau Chan
wiley   +1 more source