Results 291 to 300 of about 408,343 (365)

Pharmaceutical Processing with Supercritical Carbon Dioxide

Journal of Pharmaceutical Sciences, 1997
Replacement of traditional solvents with "environmentally benign" carbon dioxide is receiving increased attention in pharmaceutical processing. Among the reported applications, particle formation with dense carbon dioxide and the "clean" synthesis of drug compounds using carbon dioxide as a reaction medium hold immense potential for large-scale ...
B, Subramaniam, R A, Rajewski, K, Snavely   +2 more
openaire   +2 more sources

Itraconazole Formation Using Supercritical Carbon Dioxide

Drug Development and Industrial Pharmacy, 2004
A new method of preparing Itraconazole (C35H38Cl2N8O4), a synthetic triazole antifungal agent, was developed using supercritical carbon dioxide (SC CO2) while eliminating the use of toxic solvents. Dissolution amounts of the product were measured in gastric fluid and compared to those of conventional drug formulations.
Ali, Hassan, Yi-Min, Tang, James W, Ayres   +2 more
openaire   +2 more sources

Dispersion Polymerizations in Supercritical Carbon Dioxide

Science, 1994
Conventional heterogeneous dispersion polymerizations of unsaturated monomers are performed in either aqueous or organic dispersing media with the addition of interfacially active agents to stabilize the colloidal dispersion that forms. Successful stabilization of the polymer colloid during polymerization results in the formation of high ...
J M, Desimone, E E, Maury, Y Z, Menceloglu, J B, McClain, T J, Romack, J R, Combes   +5 more
openaire   +2 more sources

Polar Attributes of Supercritical Carbon Dioxide

Accounts of Chemical Research, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
Poovathinthodiyil, Raveendran, Yutaka, Ikushima, Scott L, Wallen   +2 more
openaire   +2 more sources

Olefin Metathesis in Supercritical Carbon Dioxide

Journal of the American Chemical Society, 2001
Liquid or supercritical carbon dioxide (scCO(2)) is a versatile reaction medium for ring-opening metathesis polymerization (ROMP) and ring-closing olefin metathesis (RCM) reactions using well-defined metal catalysts. The molybdenum alkylidene complex 1 and ruthenium carbenes 2 and 3 bearing PCy(3) or N-heterocyclic carbene ligands, respectively, can be
A, Fürstner, L, Ackermann, K, Beck, H, Hori, D, Koch, K, Langemann, M, Liebl, C, Six, W, Leitner   +8 more
openaire   +2 more sources

Experimental Solubility Measurements of Fenoprofen in Supercritical Carbon Dioxide

, 2020
In the current investigation, the solubility of fenoprofen as a nonsteroidal anti-inflammatory drug in supercritical CO2 (SC-CO2) is measured by employing a motorized PVT (pressure–volume–temperatu...
Samyar Zabihi, Y. Rahnama, A. Sharafi, Fatemeh Borousan, Ali Zeinolabedini Hezave, Saeed Shirazian   +5 more
semanticscholar   +1 more source

Nitrile oxide cycloadditions in supercritical carbon dioxide

Chemical Communications, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Connie K Y, Lee, Andrew B, Holmes, Bushra, Al-Duri, Gary A, Leeke, Regina C D, Santos, Jonathan P K, Seville   +5 more
openaire   +2 more sources

Homogeneous Catalysis in Supercritical Carbon Dioxide

2003
The utilization of SCFs as reaction media for metal-complex-catalyzed reactions has received growing attention in the last decade [1]. In fact, the peculiar properties of SCFs (high diffusivity, low viscosity, compressibility, tuneable solvent properties, etc) can make advantageous the use of SCFs as media for metal-complex catalyzed reactions in place
QUARANTA, Eugenio, EARLY T. R., HOLMES A. B., LEE J. K., STAMP L. M.   +4 more
openaire   +2 more sources

Supercritical Carbon Dioxide: The "Greener" Solvent

Environmental Science & Technology, 1996
It's not toxic and it doesn't harm the ozone layer, but can supercritical CO2 do the job in major industrial applications?
openaire   +2 more sources

Dissolution of uranium dioxide in supercritical fluid carbon dioxide

Chemical Communications, 2001
Uranium dioxide can be dissolved in supercritical CO2 with a CO2-philic TBP-HNO3 complexant to form a highly soluble UO2(NO3)(2).2TBP complex; this new method of dissolving UO2 that requires no water or organic solvent may have important applications for reprocessing of spent nuclear fuels and for treatment of nuclear wastes.
M D, Samsonov, C M, Wai, S C, Lee, Y, Kulyako, N G, Smart   +4 more
openaire   +2 more sources